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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: VDR promotes pancreatic cancer progression in vivo by activating CCL20-mediated M2 polarization of tumor associated macrophage

Fig. 2

VDR is associated with M2 macrophages infiltration in PAAD. (A) Heatmap of VDR expression in PAAD correlating with infiltration of 28 immune cells. (B) KEGG analysis revealed the top 20 immune system pathways that are significantly different between the VDR high and low groups. (C-D) The TIMER2.0 database system was used to analyze the correlation between VDR expression and immune cells infiltration in PAAD. (E) Immunohistochemistry was performed to detect the expressions of VDR and macrophages in PAAD. Scale bars = 300 μm. (F-G) Pearson correlation analysis was used to assess the correlation between VDR expression and macrophages infiltration

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