Fig. 2
From: JAK/STAT mediated insulin resistance in muscles is essential for effective immune response
The role of upd in immune response. A: Lamellocyte number in upd mutants compared to control animals (N = 3, n = 46–99), each dot represents number of lamellocytes in an individual larva. B: Resistance to wasp infection (N = 3, n = 43–45). The presence of a melanized wasp egg or dead wasp larva indicates resistance to wasp infection. There is a significant difference in number of surviving Drosophila larvae between upd3Δ and control and upd2/3Δ and control animals (p = ≤ 0.0001). The resistance of upd3Δ and upd2/3Δ on a high carbohydrate diet (HC) increased significantly compared to those same larvae on a standard food diet (p = ≤ 0.01) however the resistance to wasp infection did not reach the levels of control larvae. C: Lamellocyte number in upd mutants on high carbohydrate food (N = 3, n = 56–86), each dot represents number of lamellocytes in an individual larvae. **** ≤ 0.0001. N represents individual experiments, n represents biological replicates