Fig. 1

In upd mutants carbohydrates are not redirected away from muscles upon infection. A: Comparison of circulating trehalose levels of control animals and upd mutants in non-infected and infected conditions (N = 2, n = 6). B: Circulating glucose levels of upd mutants compared to controls in non-infected and infected larvae (N = 2, n = 6). C: Level of glycogen stores in muscle tissue in non-infected and infected animals (N = 2, n = 6). D: Larval locomotion: Accumulated distance traveled by control animals and upd3 mutants, with and without infection (N = 2–3, n = 18–24). A-C: Bars represent mean values, dots represent biological replicates. D: boxes represent mean values, dots represent individual larvae. ns: no significant difference, * p ≤ 0.05, ** p ≤ 0.01, **** ≤ 0.0001. N represents individual experiments, n represents biological replicates