Skip to main content
Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Interleukin-4 from curcumin-activated OECs emerges as a central modulator for increasing M2 polarization of microglia/macrophage in OEC anti-inflammatory activity for functional repair of spinal cord injury

Fig. 3

In vitro analysis of M1 and M2 polarization markers in microglial cells following exposure to proinflammatory stimuli and blockade of IL-4 signaling from aOECs. mRNA expression for M1 phenotypic genes CD86 (a), iNOS (b), IL-1β (c) and IL-6 (d) or M2 phenotypic genes CD206 (e), Arg-1 (f), YM-1 (g), IL-10 (h) using real time RT-PCR. Data are reported as means ± SEM of 3 independent experiments. *p < 0.05, **p < 0.01, and ***p < 0.001 compared with the corresponding controls

Back to article page