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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage

Fig. 7

Inhibition of STING could reverse cGAMP-induced microglial M1 type polarization both in vitro and in vivo. A Representative photomicrographs of microglia. (scale bar is 50μm). B Dual immunofluorescence staining of CD86 with Iba-1 of microglia. (scale bar is 100μm). C Western blot analysis and quantitative analyses of CD86 and CD68 expression. (** P < 0.01). D QPCR analysis of IL-6 and TNF-α. (** P < 0.01). E Flow cytometry analysis of CD86 and CD11b of microglia. F Dual immunofluorescence staining of CD86 with Iba-1 in cerebral cortex. (scale bar is 100μm). G Western blot analysis and quantitative analyses of CD86 and CD68 expression. (** P < 0.01). H QPCR analysis of IL-6 and TNF-α. (** P < 0.01)

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Cell Communication and Signaling

ISSN: 1478-811X