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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma

Fig. 1

Relationship between calcification of ACP and its surrounding anatomic structures. A, B Sagittal MR and CT scans showing tumor calcifications (yellow arrows: calcification lesions are shown by the low signal in the MR image presented in A and high density in the CT scan presented in B) located above the pituitary gland and below the hypothalamus. C The calcification lesion (yellow arrow) was closely related to the right ICA. D Under the surgical view from the extended endonasal endoscopic perspective, the calcification lesion (yellow arrow) was found to adhere to the optic chiasm and pituitary gland. Surgeons must be very careful when separating the lesion from the surrounding anatomical structures (hypothalamus, ICA and optic chiasm) to avoid serious postoperative complications. (ICA: internal carotid artery). E Calcification lesion (CL) and its precursor structure the whorl-like array cells (WA) were found in adamantinomatous craniopharyngioma sample. We can see a calcification lesion (CL) is arising from its whorl-like array cells (WA) at the central part of this image. F Squamous papillary craniopharyngioma comprising mature squamous epithelia without calcification

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