Table 2 Top 15 significantly enriched Gene Ontology biological processes under hypergravity

GO:0048598

embryonic morphogenesis

2.28*10⁻⁵

BMP4, WNT5A, FGF9, GDF5, EDN1, COL2A1, HOXD10, MSX1, LAMA5, ALDH1A3, TFAP2A, TXNRD1, FBN2

GO:0001501

skeletal system development

3.33*10⁻⁵

BMP4, WNT5A, AEBP1, FGF9, TUFT1, EDN1, COL2A1, DLK1, HOXD10, HOXC8, MSX1, TFAP2A, GPNMB

GO:0048729

tissue morphogenesis

3.83*10⁻⁵

BMP4, FOXQ1, CRYGS, PGF, LAMA5, ALDH1A3, TGM3, TFAP2A, TXNRD1, CA2

GO:0048736

appendage development

4.16*10⁻⁵

WNT5A, MSX1, MEOX2, FGF9, GDF5, COL2A1, FBN2, HOXD10

GO:0060173

limb development

4.16*10⁻⁵

WNT5A, MSX1, MEOX2, FGF9, GDF5, COL2A1, FBN2, HOXD10

GO:0035295

tube development

1.79*10⁻⁴

WNT5A, BMP4, FGF9, PGF, LAMA5, EDN1, HOPX, TFAP2A, HHIP, CXCL12

GO:0035107

appendage morphogenesis

2.81*10⁻⁴

WNT5A, MSX1, FGF9, GDF5, COL2A1, FBN2, HOXD10

GO:0035108

limb morphogenesis

2.81*10⁻⁴

WNT5A, MSX1, FGF9, GDF5, COL2A1, FBN2, HOXD10

GO:0002009

morphogenesis of an epithelium

3.13*10⁻⁴

BMP4, CRYGS, PGF, LAMA5, ALDH1A3, TFAP2A, CA2

GO:0001525

angiogenesis

4.01*10⁻⁴

BMP4, MEOX2, FGF9, PGF, LAMA5, EDN1, CXCL12, ANGPTL4

GO:0060541

respiratory system development

4.49*10⁻⁴

WNT5A, BMP4, FGF9, LAMA5, ALDH1A3, HOPX, HHIP

GO:0051216

cartilage development

5.59*10⁻⁴

WNT5A, BMP4, MSX1, FGF9, EDN1, COL2A1

GO:0007155

cell adhesion

5.96*10⁻⁴

HAPLN1, AEBP1, EPDR1, CPXM2, COL2A1, CDH2, EMILIN2, CXCL12, OMD, PGM5, LAMA5, ITGB1BP1, MSLN, LAMC2, GPNMB, THBS2, NTM

GO:0022610

biological adhesion

6.05*10⁻⁴

HAPLN1, AEBP1, EPDR1, CPXM2, COL2A1, CDH2, EMILIN2, CXCL12, OMD, PGM5, LAMA5, ITGB1BP1, MSLN, LAMC2, GPNMB, THBS2, NTM

GO:0048514

blood vessel morphogenesis

6.81*10⁻⁴

BMP4, MEOX2, FGF9, PGF, LAMA5, EDN1, CDH2, CXCL12, ANGPTL4