Figure 5
From: Function, regulation and pathological roles of the Gab/DOS docking proteins
The Phosphomaps of human Gab1 and Gab2. This cartoon is based on information from sources cited in the main text and on the Phosphosite homepage http://www.phosphosite.org. Phosphotyrosine residues involved or strongly implicated in the recruitment of the SH2 domain containing effectors Shp2, p85, Crk and PLCγ are indicated. Ser/Thr-residues phosphorylated in an ERK- or PI3K-dependent manner are also shown.