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Figure 9 | Cell Communication and Signaling

Figure 9

From: Integration of Myeloblastosis Associated Virus proviral sequences occurs in the vicinity of genes encoding signaling proteins and regulators of cell proliferation

Figure 9

Detection of CCN3 sequences in normal and tumor DNA. RNA species purified from normal kidney cells (N) and tumor cells (T) were labeled (see materials and methods) and used to probe BAC15 DNA that harbors the ccn3 gene. The DNA fragments detected with the RNA species expressed in tumor cells (panel B) confirm that ccn3 is overexpressed in the tumor context. As a control, the DNA fragments from BAC15 were hybridized with radiolabeled chicken ccn3 cDNA. The DNAfragments which are detected correspond to exons encoding the ccn3 RNA species that are highly expressed in the tumor context (panel C).

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Cell Communication and Signaling

ISSN: 1478-811X