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Figure 2 | Cell Communication and Signaling

Figure 2

From: Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary target

Figure 2

Dose dependent effects of cucurbitacin D, E and I on the actin cytoskeletal structures in MCF7 breast cancer cells. 4 hours after cucurbitacin D (CuD), cucurbitacin E (CuE) or cucurbitacin I (CuI) treatment at doses from 1 nM to 1 μM, cells were fixed, permeabilized and stained with Texas Red-conjugated phalloidin and DAPI. All images were acquired at identical magnification, but adjusted to produce images with equivalent phalloidin intensities for visualization of actin structures.

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Cell Communication and Signaling

ISSN: 1478-811X