Table 1 Potential binding partners of Sec7 and its domains

Membrane trafficking, membrane associated processes

DDB0237869

cog3, oligomeric Golgi complex component

DDB0237794

osbH, oxysterol binding

DDB0185207

vatB, v-ATPase

DDB0234266

vatH, v-ATPase

DDB0233782

Present in macropinocytic proteome; conserved; transporter?

DDB0185052

nsfA, N-ethylmaleimide-sensitive fusion protein

DDB0234240

p3d1, delta adaptin (endosomal membrane)

DDB0234067

Ap1b1, adaptor-related protein complex 1, beta 1 subunit, beta adaptin, highly similar to AP-1 complex subunit beta-1 (AP1B1) and AP-2 complex subunit beta-1 (AP2B1), which play a role in clathrin-dependent protein sorting

DDB0304807

tgrO4, immunoglobulin E-set domain-containing protein, tgr (tiger) = Transmembrane, IPT, IG, E-set, Repeat protein

DDB0233801

copG, adaptin N-terminal domain-containing protein

coatomer protein complex gamma subunit

gamma-COP

DDB0306480

Single C-terminal TM

DDB0238597

Dnajc13, DnaJ (Hsp40) homolog, subfamily C, member 13, very similar to the mammalian DnaJ homolog subfamily C member 13, required in D. melanogaster (Rme-8) for receptor-mediated endocytosis 8

DDB0185049

myoI, class VII unconventional myosin

myosin VII, similar to the conserved MYO7A; unconventional myosin required in Dictyostelium for phagocytosis and substrate adhesion, interacts with talA

DDB0234198

vps13A, vacuolar protein sorting-associated protein 13 family protein, putative ortholog of S. cerevisiae VPS13, involved in vacuolar protein sorting and protein-Golgi retention

Related to signal transduction

DDB0191258

pppA, protein phosphatase 2A subunit A

DDB0235201

guanylate-binding protein

GTP-binding protein, 92 kDa

DDB0233622

zizB, DOCK family protein, putative guanine nucleotide exchange factor (GEF)

DDB0233623

zizA, DOCK family protein, putative guanine nucleotide exchange factor (GEF)

Cytoskeleton

DDB0201554

abpC, filamin

DDB0233781

Centrosomal, 80 kDa

DDB0191169

tubB, tubulin

DDB0191115

corA

DDB0185096

cytoplasmic dynein heavy chain,

dynein beta chain, flagellar outer arm

DDB0185049

myoI class VII unconventional myosin

myosin VII, similar to the conserved MYO7A; unconventional myosin required in Dictyostelium for phagocytosis and substrate adhesion, interacts with talA

DDB0191103

cortexillin I