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  1. The effectiveness of anti-programmed cell death protein 1(PD-1)/programmed cell death 1 ligand 1(PD-L1) therapy in treating certain types of cancer is associated with the level of PD-L1. However, this relation...

    Authors: Xiaofeng Dai, Zhipeng Wu, Ruiwen Ruan, Jingyi Chen, Chunye Huang, Wan Lei, Yangyang Yao, Li Li, Xiaomei Tang, Jianping Xiong, Miao Feng and Jun Deng
    Citation: Cell Communication and Signaling 2024 22:168
  2. Sexual dimorphism has been observed in the incidence and prognosis of colorectal cancer (CRC), with men generally exhibiting a slightly higher incidence than women. Research suggests that this difference may b...

    Authors: Zihong Wu, Yuqing Huang, Renyi Zhang, Chuan Zheng, Fengming You, Min Wang, Chong Xiao and Xueke Li
    Citation: Cell Communication and Signaling 2024 22:167
  3. Clinical and experimental studies have shown that the myocardial inflammatory response during pathological events varies between males and females. However, the cellular and molecular mechanisms of these sex d...

    Authors: Marie Louise Ndzie Noah, Richard Mprah, Prosperl Ivette Wowui, Adebayo Oluwafemi Adekunle, Joseph Adu-Amankwaah, Rubin Tan, Zheng Gong, Tao Li, Lu Fu, Jeremiah Ong’achwa Machuki, Shijie Zhang and Hong Sun
    Citation: Cell Communication and Signaling 2024 22:166
  4. Among the mechanisms of mitochondrial quality control (MQC), generation of mitochondria-derived vesicles (MDVs) is a process to avoid complete failure of mitochondria determining lysosomal degradation of mitoc...

    Authors: Sinforosa Gagliardi, Marco Mitruccio, Riccardo Di Corato, Roberta Romano, Alessandra Aloisi, Rosaria Rinaldi, Pietro Alifano, Flora Guerra and Cecilia Bucci
    Citation: Cell Communication and Signaling 2024 22:165
  5. Pancreatic neuroendocrine tumors (PanNETs), though uncommon, have a high likelihood of spreading to other body parts. Previously, the genetic diversity and evolutionary patterns in metastatic PanNETs were not ...

    Authors: Yu Jiang, Yi-han Dong, Shi-wei Zhao, Dong-yu Liu, Ji-yang Zhang, Xiao-ya Xu, Hao Chen, Hao Chen and Jia-bin Jin
    Citation: Cell Communication and Signaling 2024 22:164

    The Correction to this article has been published in Cell Communication and Signaling 2024 22:181

  6. Asparagine, an important amino acid in mammals, is produced in several organs and is widely used for the production of other nutrients such as glucose, proteins, lipids, and nucleotides. Asparagine has also be...

    Authors: Qiong Yuan, Liyang Yin, Jun He, Qiting Zeng, Yuxin Liang, Yingying Shen and Xuyu Zu
    Citation: Cell Communication and Signaling 2024 22:163
  7. Microglia/macrophages are major contributors to neuroinflammation in the central nervous system (CNS) injury and exhibit either pro- or anti-inflammatory phenotypes in response to specific microenvironmental s...

    Authors: Jianbin Guo, Xiangwen Tang, Peng Deng, Hao Hui, Bo Chen, Jing An, Gaorong Zhang, Kuohao Shi, Jinchao Wang, Yuqing He, Dingjun Hao and Hao Yang
    Citation: Cell Communication and Signaling 2024 22:162
  8. Breast cancer is the most common cancer in women worldwide. Triple-negative breast cancer (TNBC) is especially aggressive and associated with high metastasis. The aetiology of TNBC is heterogeneous and charact...

    Authors: Hannes Bongartz, Nora Mehwald, Elena A. Seiß, Tim Schumertl, Norbert Naß and Anna Dittrich
    Citation: Cell Communication and Signaling 2024 22:161
  9. Estrogen deficiency-mediated hyperactive osteoclast represents the leading role during the onset of postmenopausal osteoporosis. The activation of a series of signaling cascades triggered by RANKL-RANK interac...

    Authors: Xiaole Peng, Tianhao Wang, Qing Wang, Yuhu Zhao, Hao Xu, Huilin Yang, Ye Gu, Yunxia Tao, Bangsheng Yan, Yaozeng Xu and Dechun Geng
    Citation: Cell Communication and Signaling 2024 22:160
  10. Heterotopic ossification (HO) is a pathological process in which ectopic bone develops in soft tissues within the skeletal system. Endochondral ossification can be divided into the following types of acquired ...

    Authors: Fangzhou Liu, Yike Zhao, Yiran Pei, Fengyu Lian and Hui Lin
    Citation: Cell Communication and Signaling 2024 22:159
  11. BMP9 and BMP10 are two major regulators of vascular homeostasis. These two ligands bind with high affinity to the endothelial type I kinase receptor ALK1, together with a type II receptor, leading to the direc...

    Authors: Mohammad Al Tarrass, Lucid Belmudes, Dzenis Koça, Valentin Azemard, Hequn Liu, Tala Al Tabosh, Delphine Ciais, Agnès Desroches-Castan, Christophe Battail, Yohann Couté, Claire Bouvard and Sabine Bailly
    Citation: Cell Communication and Signaling 2024 22:158
  12. O-GlcNAcylation modification affects multiple physiological and pathophysiolocal functions of cells. Altered O-GlcNAcylation was reported to participate in antivirus response. Stimulator of interferon genes (S...

    Authors: Yujia Li, Wang An, Liyuan Lu, Jiali Yuan, Danhui Wu, Qi Yang, Jinrong Guo, Jingyu Yang, Mengjie Liu, Kaiyue He, Xinyuan Lei and Zhi-Xiang Xu
    Citation: Cell Communication and Signaling 2024 22:157
  13. Exosomes are nanoscale extracellular vesicles present in bodily fluids that mediate intercellular communication by transferring bioactive molecules, thereby regulating a range of physiological and pathological...

    Authors: Min Xiong, Zhen Chen, Jiaqi Tian, Yanjie Peng, Dandan Song, Lin Zhang and Yulan Jin
    Citation: Cell Communication and Signaling 2024 22:156
  14. Vascular endothelial cells are pivotal in the pathophysiological progression following spinal cord injury (SCI). The UTX (Ubiquitously Transcribed Tetratripeptide Repeat on Chromosome X) serves as a significan...

    Authors: Yudong Liu, Zixiang Luo, Yong Xie, Yi Sun, Feifei Yuan, Liyuan Jiang, Hongbin Lu and Jianzhong Hu
    Citation: Cell Communication and Signaling 2024 22:155
  15. Although GqPCR activation often leads to cell survival by activating the PI3K/AKT pathway, it was previously shown that in several cell types AKT activity is reduced and leads to JNK activation and apoptosis. ...

    Authors: Guy Nadel, Zhong Yao, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Tamar Ziv, Zvi Naor, Arie Admon and Rony Seger
    Citation: Cell Communication and Signaling 2024 22:154
  16. Gastrointestinal stromal tumor (GIST) is the most common sarcoma located in gastrointestinal tract and derived from the interstitial cell of Cajal (ICC) lineage. Both ICC and GIST cells highly rely on KIT sign...

    Authors: Shishan Zhou, Omar Abdihamid, Fengbo Tan, Haiyan Zhou, Heli Liu, Zhi Li, Sheng Xiao and Bin Li
    Citation: Cell Communication and Signaling 2024 22:153
  17. Germline mutations of E-cadherin contribute to hereditary diffuse gastric cancer (HDGC) and congenital malformations, such as oral facial clefts (OFC). However, the molecular mechanisms through which E-cadheri...

    Authors: Joana Pereira, Soraia Melo, Rui M. Ferreira, Patrícia Carneiro, Vítor Yang, André F. Maia, João Carvalho, Ceu Figueiredo, José Carlos Machado, Eurico Morais-de-Sá, Raquel Seruca and Joana Figueiredo
    Citation: Cell Communication and Signaling 2024 22:152
  18. Coenzyme Q0 (CoQ0), a novel quinone derivative of Antrodia camphorata, has been utilized as a therapeutic agent (including antioxidant, anti-inflammatory, antiangiogenic, antiatherosclerotic, and anticancer agent...

    Authors: You-Cheng Hseu, Jou-Tsen Yeh, Chithravel Vadivalagan, Siang-Jyun Chen, Yugandhar Vudhya Gowrisankar, Sudhir Pandey, Yuan-Tai Hsu, Hung-Rong Yen, Hui-Chi Huang, Jhih-Hsuan Hseu and Hsin-Ling Yang
    Citation: Cell Communication and Signaling 2024 22:151
  19. Small extracellular vesicles (EVs), exemplified by exosomes, mediate intercellular communication by transporting proteins, mRNAs, and miRNAs. Post-translational modifications are involved in controlling small ...

    Authors: Mengyuan Qu, Xinyu Liu, Xiaotong Wang, Zili Li, Liquan Zhou and Honggang Li
    Citation: Cell Communication and Signaling 2024 22:150
  20. Apoptosis plays a pivotal role in pathogen elimination and maintaining homeostasis. However, viruses have evolved strategies to evade apoptosis, enabling their persistence within the host. Z-DNA binding protei...

    Authors: Jianhao Zhan, Jisheng Wang, Yuqing Liang, Lisha Wang, Le Huang, Shanshan Liu, Xiaoping Zeng, Erming Zeng and Hongmei Wang
    Citation: Cell Communication and Signaling 2024 22:149
  21. Tubulointerstitial kidney disease associated microenvironmental dysregulation, like acidification, inflammation and fibrosis, affects tubule cells and fibroblasts. Micromilieu homeostasis influences intracellu...

    Authors: Marie-Christin Schulz, Michael Kopf and Michael Gekle
    Citation: Cell Communication and Signaling 2024 22:148
  22. Patients with Alzheimer’s disease (AD) are often co-morbid with unprovoked seizures, making clinical diagnosis and management difficult. Although it has an important role in both AD and epilepsy, abnormal γ-am...

    Authors: Rui Mao, Mengsha Hu, Xuan Liu, Lei Ye, Bingsong Xu, Min Sun, Siyi Xu, Wenxuan Shao, Yi Tan, Yun Xu, Feng Bai and Shu Shu
    Citation: Cell Communication and Signaling 2024 22:147
  23. Paraquat (PQ) is an irreplaceable insecticide in many countries for the advantage of fast-acting and broad-spectrum. However, PQ was classified as the most prevailing poisoning substance for suicide with no sp...

    Authors: Jing Du, Lingyan Yu, Xinyi Yang, Fangchun Shao, Jun Xia, Weidong Jin, Yinhao Zhang, Guojie Lei, Ying Wang, Yanchun Li and Jun Zhang
    Citation: Cell Communication and Signaling 2024 22:146
  24. ZEB1, a core transcription factor involved in epithelial-mesenchymal transition (EMT), is associated with aggressive cancer cell behavior, treatment resistance, and poor prognosis across various tumor types. S...

    Authors: Samlai Vedovatto, Fernanda Dittrich Oliveira, Luiza Cherobini Pereira, Thamiris Becker Scheffel, Liziane Raquel Beckenkamp, Ana Paula Santin Bertoni, Márcia Rosângela Wink and Guido Lenz
    Citation: Cell Communication and Signaling 2024 22:145
  25. Solid tumors such as glioblastoma (GBM) exhibit hypoxic zones that are associated with poor prognosis and immunosuppression through multiple cell intrinsic mechanisms. However, release of extracellular vesicle...

    Authors: Stoyan Tankov, Marija Petrovic, Marc Lecoultre, Felipe Espinoza, Nadia El-Harane, Viviane Bes, Sylvie Chliate, Darel Martinez Bedoya, Olivier Jordan, Gerrit Borchard, Denis Migliorini, Valérie Dutoit and Paul R. Walker
    Citation: Cell Communication and Signaling 2024 22:144
  26. Calcium is a ubiquitous intracellular messenger that regulates the expression of various genes involved in cell proliferation, differentiation, and motility. The involvement of calcium in diverse metabolic pat...

    Authors: Laxman Manandhar, Raghbendra Kumar Dutta, Pradeep Devkota, Arun Chhetri, Xiaofan Wei, Channy Park, Hyug Moo Kwon and Raekil Park
    Citation: Cell Communication and Signaling 2024 22:142
  27. Lipids are regulators of insulitis and β-cell death in type 1 diabetes development, but the underlying mechanisms are poorly understood. Here, we investigated how the islet lipid composition and downstream sig...

    Authors: Soumyadeep Sarkar, Cailin Deiter, Jennifer E. Kyle, Michelle A. Guney, Dylan Sarbaugh, Ruichuan Yin, Xiangtang Li, Yi Cui, Mireia Ramos-Rodriguez, Carrie D. Nicora, Farooq Syed, Jonas Juan-Mateu, Charanya Muralidharan, Lorenzo Pasquali, Carmella Evans-Molina, Decio L. Eizirik…
    Citation: Cell Communication and Signaling 2024 22:141
  28. Hostile microenvironment of cancer cells provoke a stressful condition for endoplasmic reticulum (ER) and stimulate the expression and secretion of ER chaperones, leading to tumorigenic effects. However, the m...

    Authors: Jie Jia, Lianhui Zhu, Xihua Yue, Shuocheng Tang, Shuaiyang Jing, Chuanting Tan, Yulei Du, Jingkai Gao, Intaek Lee and Yi Qian
    Citation: Cell Communication and Signaling 2024 22:140
  29. Malaria remains a global health burden, and the emergence and increasing spread of drug resistance to current antimalarials poses a major challenge to malaria control. There is an urgent need to find new drugs...

    Authors: Peng Gao, Jianyou Wang, Huan Tang, Huanhuan Pang, Jiemei Liu, Chen Wang, Fei Xia, Honglin Chen, Liting Xu, Junzhe Zhang, Lixia Yuan, Guang Han, Jigang Wang and Gang Liu
    Citation: Cell Communication and Signaling 2024 22:139
  30. Applications of nonthermal plasma have expanded beyond the biomedical field to include antibacterial, anti-inflammatory, wound healing, and tissue regeneration. Plasma enhances epithelial cell repair; however,...

    Authors: Sung Un Kang, Haeng Jun Kim, Sukhwal Ma, Doo-Yi Oh, Jeon Yeob Jang, Chorong Seo, Yun Sang Lee and Chul-Ho Kim
    Citation: Cell Communication and Signaling 2024 22:138
  31. Protein phosphorylation is one of the most prevalent posttranslational modifications involved in molecular control of cellular processes, and is mediated by over 520 protein kinases in humans and other mammals...

    Authors: Brian G. Poll, Kirby T. Leo, Venky Deshpande, Nipun Jayatissa, Trairak Pisitkun, Euijung Park, Chin-Rang Yang, Viswanathan Raghuram and Mark A. Knepper
    Citation: Cell Communication and Signaling 2024 22:137
  32. Diabetic kidney disease (DKD) is a long-term and serious complication of diabetes that affects millions of people worldwide. It is characterized by proteinuria, glomerular damage, and renal fibrosis, leading t...

    Authors: Shiwan Hu, Xing Hang, Yu Wei, Han Wang, Lili Zhang and Linhua Zhao
    Citation: Cell Communication and Signaling 2024 22:136
  33. Ovarian stimulation (OS) during assisted reproductive technology (ART) appears to be an independent factor influencing the risk of low birth weight (LBW). Previous studies identified the association between LB...

    Authors: Xueyan Lu, Jiaqin Mao, Chenxi Qian, Hui Lei, Fei Mu, Huijun Sun, Song Yan, Zheng Fang, Jie Lu, Qian Xu, Jie Dong, Danjie Su, Jingjing Wang, Ni Jin, Shuqiang Chen and Xiaohong Wang
    Citation: Cell Communication and Signaling 2024 22:135
  34. Pancreatic ductal adenocarcinoma is an aggressive cancer type with one of the lowest survival rates due to late diagnosis and the absence of effective treatments. A better understanding of PDAC biology will he...

    Authors: Sandy Anania, Martin Farnir, Raphaël Peiffer, Yasmine Boumahd, Marc Thiry, Ferman Agirman, Naima Maloujahmoum, Akeila Bellahcène and Olivier Peulen
    Citation: Cell Communication and Signaling 2024 22:133
  35. Abnormal inflammatory states in the brain are associated with a variety of brain diseases. The dynamic changes in the number and function of immune cells in cerebrospinal fluid (CSF) are advantageous for the e...

    Authors: Xiaotong Xu, Yi Han, Binlong Zhang, Quanzhong Ren, Juan Ma and Sijin Liu
    Citation: Cell Communication and Signaling 2024 22:132
  36. Malignant tumours seriously threaten human life and health, and effective treatments for cancer are still being explored. The ability of SHC SH2 domain-binding protein 1 (SHCBP1) to induce cell cycle disturban...

    Authors: Mei Zhou, Limin Duan, Jiangbin Chen, Yumei Li, Zhengrong Yin, Siwei Song, Yaqi Cao, Ping Luo, Fan Hu, Guanghai Yang, Juanjuan Xu, Tingting Liao and Yang Jin
    Citation: Cell Communication and Signaling 2024 22:131
  37. In recent decades, emerging data have highlighted the critical role of extracellular vesicles (EVs), especially (exosomes) Exos, in the progression and development of several cancer types. These nano-sized ves...

    Authors: Zahra Abbasi-Malati, Seyed Ghader Azizi, Soheil Zamen Milani, Zeinab Aliyari Serej, Narges Mardi, Zahra Amiri, Zohreh Sanaat and Reza Rahbarghazi
    Citation: Cell Communication and Signaling 2024 22:130
  38. Extracellular vesicles (EVs), including microvesicles, hold promise for the management of bladder urothelial carcinoma (BLCA), particularly because of their utility in identifying therapeutic targets and their...

    Authors: Vijay Kumar Boddu, Piet Zamzow, Mario Wolfgang Kramer, Axel S. Merseburger, Sivahari Prasad Gorantla, Matthias Klinger, Lena Cramer, Thorben Sauer, Timo Gemoll, Nikolas von Bubnoff, Frank Gieseler and Masoud Darabi
    Citation: Cell Communication and Signaling 2024 22:129
  39. In pathologies including cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are underway to target this pathw...

    Authors: Alex S. Choi, Laura M. Jenkins-Lane, Wade Barton, Asha Kumari, Carly Lancaster, Calen Raulerson, Hao Ji, Diego Altomare, Mark D. Starr, Regina Whitaker, Rebecca Phaeton, Rebecca Arend, Michael Shtutman, Andrew B. Nixon, Nadine Hempel, Nam Y. Lee…
    Citation: Cell Communication and Signaling 2024 22:128
  40. All-trans retinoic acid (ATRA) is the most relevant and functionally active metabolite of Vitamin-A. From a therapeutic standpoint, ATRA is the first example of pharmacological agent exerting its anti-tumor acti...

    Authors: Maria Azzurra Caricasulo, Adriana Zanetti, Mineko Terao, Enrico Garattini and Gabriela Paroni
    Citation: Cell Communication and Signaling 2024 22:127
  41. Extensive research in countries with high sociodemographic indices (SDIs) to date has shown that coronavirus disease 2019 (COVID-19) may be directly associated with more severe outcomes among patients living w...

    Authors: Sareh Kakavandi, Bahareh Hajikhani, Paniz Azizi, Fatemeh Aziziyan, Mohsen Nabi-Afjadi, Marzieh Ramezani Farani, Hamidreza Zalpoor, Maryam Azarian, Mahdiyar Iravani Saadi, Behrouz Gharesi-Fard, Evangelos Terpos, Iman Zare and Mohammad Motamedifar
    Citation: Cell Communication and Signaling 2024 22:126
  42. The activation of peroxisome proliferator-activated receptor (PPAR)-γ has been extensively shown to attenuate inflammatory responses in conditions such as asthma, acute lung injury, and acute respiratory distr...

    Authors: I-Ta Lee, Chien-Chung Yang and Chuen-Mao Yang
    Citation: Cell Communication and Signaling 2024 22:125
  43. Autophagy is a self-renewal mechanism that maintains homeostasis and can promote tissue regeneration by regulating inflammation, reducing oxidative stress and promoting cell differentiation. The interaction be...

    Authors: Yan Wu, Luxin Li, Zuojun Ning, Changrong Li, Yongkui Yin, Kaiyuan Chen, Lu Li, Fei Xu and Jie Gao
    Citation: Cell Communication and Signaling 2024 22:124
  44. Meningitic Escherichia coli (E. coli) is the major etiological agent of bacterial meningitis, a life-threatening infectious disease with severe neurological sequelae and high mortality. The major cause of central...

    Authors: Jinrui Sun, Ruicheng Yang, Jiyang Fu, Dong Huo, Xinyi Qu, Chen Tan, Huanchun Chen and Xiangru Wang
    Citation: Cell Communication and Signaling 2024 22:123
  45. Cells that are exposed to harmful genetic damage, either from internal or external sources, may undergo senescence if they are unable to repair their DNA. Senescence, characterized by a state of irreversible g...

    Authors: Nicola Alessio, Domenico Aprile, Gianfranco Peluso, Valeria Mazzone, Deanira Patrone, Giovanni Di Bernardo and Umberto Galderisi
    Citation: Cell Communication and Signaling 2024 22:122
  46. R140Q mutation in isocitrate dehydrogenase 2 (IDH2) promotes leukemogenesis. Targeting IDH2/R140Q yields encouraging therapeutic effects in the clinical setting. However, therapeutic resistance occurs in 12% o...

    Authors: Jie Yang, Jiao Chen, Jingjie Chang, Xiaoyan Sun, Qingyun Wei, Xueting Cai and Peng Cao
    Citation: Cell Communication and Signaling 2024 22:116
  47. Sirtuins, which are NAD+-dependent class III histone deacetylases, are involved in various biological processes, including DNA damage repair, immune inflammation, oxidative stress, mitochondrial homeostasis, auto...

    Authors: Qi Jin, Fang Ma, Tongtong Liu, Liping Yang, Huimin Mao, Yuyang Wang, Liang Peng, Ping Li and Yongli Zhan
    Citation: Cell Communication and Signaling 2024 22:114
  48. Psoriasis is an immune-mediated inflammatory skin disease, involving a complex interplay between genetic and environmental factors. Previous studies have demonstrated that genetic factors play a major role in ...

    Authors: Suwen Liu, Mengwen He, Jian Jiang, Xiaoru Duan, Bao Chai, Jingyu Zhang, Qingxiao Tao and Hongxiang Chen
    Citation: Cell Communication and Signaling 2024 22:108

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 8.2
    5-year Journal Impact Factor: 8.0
    Source Normalized Impact per Paper (SNIP): 1.569
    SCImago Journal Rank (SJR): 2.308

    Speed 2023
    Submission to first editorial decision (median days): 5
    Submission to acceptance (median days): 83

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    Downloads: 1,766,710
    Altmetric mentions: 2,366