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  1. Sepsis is a severe systemic inflammatory disorder manifested by a dysregulated immune response to infection and multi-organ failure. Numerous studies have shown that elevated ferritin levels exist as an essent...

    Authors: Hao Zhang, Dan Wu, Yanghanzhao Wang, Yuxin Shi, Yuwen Shao, Fu Zeng, Charles B. Spencer, Lilibeth Ortoga, Dehua Wu and Changhong Miao
    Citation: Cell Communication and Signaling 2024 22:97
  2. The remarkable regenerative capacity of the liver enables recovery after radical Hepatocellular carcinoma (HCC) resection. After resection, macrophages secrete interleukin 6 and hepatocyte growth factors to pr...

    Authors: Yiyuan Chen, Lijun Meng, Nan Xu, Huan Chen, Xuyong Wei, Di Lu, Shuai Wang and Xiao Xu
    Citation: Cell Communication and Signaling 2024 22:95
  3. Interferon-γ-inducible protein of 10 kDa (IP-10/CXCL10) is a dual-function CXC chemokine that coordinates chemotaxis of activated T cells and natural killer (NK) cells via interaction with its G protein-couple...

    Authors: Luna Dillemans, Karen Yu, Alexandra De Zutter, Sam Noppen, Mieke Gouwy, Nele Berghmans, Lisa Verhallen, Mirre De Bondt, Lotte Vanbrabant, Stef Brusselmans, Erik Martens, Dominique Schols, Patrick Verschueren, Mette M. Rosenkilde, Pedro Elias Marques, Sofie Struyf…
    Citation: Cell Communication and Signaling 2024 22:94
  4. Physical exercise directly stretching the peripheral nerve promotes nerve regeneration; however, its action mechanism remains elusive. Our present study aimed to investigate the effects of mechanosensitive cha...

    Authors: Fangzhen Shan, Nannan Zhang, Xiaoying Yao, Yi Li, Zihao Wang, Chuanji Zhang and Yuzhong Wang
    Citation: Cell Communication and Signaling 2024 22:93
  5. Inherited retinal degenerations (IRDs) are a group of untreatable and commonly blinding diseases characterized by progressive photoreceptor loss. IRD pathology has been linked to an excessive activation of cyc...

    Authors: Jie Yan, Lan Wang, Qian-Lu Yang, Qian-Xi Yang, Xinyi He, Yujie Dong, Zhulin Hu, Mathias W. Seeliger, Kangwei Jiao and François Paquet-Durand
    Citation: Cell Communication and Signaling 2024 22:92
  6. Colorectal cancer (CRC) is a significant public health concern, and its development is associated with mitochondrial dysfunction. Mitochondria can adapt to the high metabolic demands of cancer cells owing to t...

    Authors: Zihong Wu, Chong Xiao, Jing Long, Wenbo Huang, Fengming You and Xueke Li
    Citation: Cell Communication and Signaling 2024 22:91
  7. Enhancing protein stability holds paramount significance in biotechnology, therapeutics, and the food industry. Circular permutations offer a distinctive avenue for manipulating protein stability while keeping...

    Authors: Tatiana N. Melnik, Maria A. Majorina, Daria E. Vorobeva, Galina S. Nagibina, Victoria R. Veselova, Ksenia A. Glukhova, Marina A. Pak, Dmitry N. Ivankov, Vladimir N. Uversky and Bogdan S. Melnik
    Citation: Cell Communication and Signaling 2024 22:90
  8. The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) causes ER stress and activates the unfolded protein response (UPR). As an adaptive cellular response to hostile microenviron...

    Authors: Jiang He, You Zhou and Lunquan Sun
    Citation: Cell Communication and Signaling 2024 22:89
  9. Retinal ganglion cell (RGC) degeneration and death cause vision loss in patients with glaucoma. Regulated cell death, once initiated, is generally considered to be an irreversible process. Recently, we showed ...

    Authors: Wenting You, Kèvin Knoops, Iris Boesten, Tos T. J. M. Berendschot, Marc A. M. J. van Zandvoort, Birke J. Benedikter, Carroll A. B. Webers, Chris P. M. Reutelingsperger and Theo G. M. F. Gorgels
    Citation: Cell Communication and Signaling 2024 22:88
  10. Arginyltransferase (Ate1) orchestrates posttranslational protein arginylation, a pivotal regulator of cellular proteolytic processes. In eukaryotic cells, two interconnected systems—the ubiquitin proteasome sy...

    Authors: Laura V. Bonnet, Anabela Palandri, Jesica B. Flores-Martin and Marta E. Hallak
    Citation: Cell Communication and Signaling 2024 22:87
  11. Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver diseases and has emerged as the leading factor in the pathogenesis of hepatocellular carcinoma (HCC). MyD88 contributes to the develop...

    Authors: Yu Liu, Haiqiang Chen, Xuanxuan Yan, Jie Zhang, Zhenzhong Deng, Maosheng Huang, Jianchun Gu and Jinhua Zhang
    Citation: Cell Communication and Signaling 2024 22:86
  12. K-Ras is the most frequently mutated Ras variant in pancreatic, colon and non-small cell lung adenocarcinoma. Activating mutations in K-Ras result in increased amounts of active Ras-GTP and subsequently a hype...

    Authors: Rebekka Geißert, Angela Lammert, Stefanie Wirth, Rabea Hönig, Dirk Lohfink, Monika Unger, Denis Pek, Konstantin Schlüter, Theresa Scheftschik, Daniel J. Smit, Manfred Jücker, Andre Menke and Klaudia Giehl
    Citation: Cell Communication and Signaling 2024 22:85
  13. Alzheimer’s disease (AD), affecting many elders worldwide, is characterized by A-beta and tau-related cognitive decline. Accumulating evidence suggests that brain iron accumulation is an important characterist...

    Authors: Yong Zhang, Weiyi Qian, Yitong Zhang, Yan Ma, Jiamin Qian, Jinping Li, Xun Wei, Yan Long and Xiangyuan Wan
    Citation: Cell Communication and Signaling 2024 22:84
  14. Tumor cells frequently suffer from endoplasmic reticulum (ER) stress. Previous studies have extensively elucidated the role of tumorous unfolded protein response in melanoma cells, whereas the effect on tumor ...

    Authors: Yuqi Yang, Sijia Wang, Xiang-xu Wang, Sen Guo, Huina Wang, Qiong Shi, Yangzi Tian, Hao Wang, Tao Zhao, Hengxiang Zhang, Baolu Zhang, Tianwen Gao, Chunying Li, Xiuli Yi and Weinan Guo
    Citation: Cell Communication and Signaling 2024 22:83
  15. As a dual-function metabolite, succinate has emerged in cell function and plays a key signaling role in linking mitochondrial function to other cellular functions. Succinate accumulation in the cytoplasm is co...

    Authors: Qi Tian, Jingyao Ruan, Yuning Wang, Yinping Xiao, Qi Cheng, Yun Chen, Mingqing Li, Kaikai Chang and Xiaofang Yi
    Citation: Cell Communication and Signaling 2024 22:82
  16. Previous research has revealed that the 18 glycoside hydrolase gene family (GH18) member Chitinase 3-like 1 (Chi3l1) can regulate osteoclast differentiation and bone resorption. However, its downstream recepto...

    Authors: Weifeng Xu, Rui Chao, Xinru Xie, Yi Mao, Xinwei Chen, Xuzhuo Chen and Shanyong Zhang
    Citation: Cell Communication and Signaling 2024 22:81
  17. Every single cell can communicate with other cells in a paracrine manner via the production of nano-sized extracellular vesicles. This phenomenon is conserved between prokaryotic and eukaryotic cells. In eukar...

    Authors: Halimeh Mobarak, Farzin Javid, Maryam Taghavi Narmi, Narges Mardi, Fatemeh Sadeghsoltani, Parisa Khanicheragh, Samaneh Narimani, Mahdi Mahdipour, Emel Sokullu, Ferzane Valioglu and Reza Rahbarghazi
    Citation: Cell Communication and Signaling 2024 22:80
  18. N1-methyladenosine (m1A) is a post-transcriptionally modified RNA molecule that plays a pivotal role in the regulation of various biological functions and activities. Especially in cancer cell invasion, prolif...

    Authors: Yafeng Liu, Shujun Zhang, Xiaohui Gao, Yi Ru, Xinyu Gu and Xinjun Hu
    Citation: Cell Communication and Signaling 2024 22:79
  19. Renal fibrosis significantly contributes to the progressive loss of kidney function in chronic kidney disease (CKD), with alternatively activated M2 macrophages playing a crucial role in this progression. The ...

    Authors: Min Pu, Jing Zhang, Fuyan Hong, Yan Wang, Chengwei Zhang, Yongcheng Zeng, Zhenzhen Fang, Weiwei Qi, Xia Yang, Guoquan Gao and Ti Zhou
    Citation: Cell Communication and Signaling 2024 22:78
  20. AXIN1, has been initially identified as a prominent antagonist within the WNT/β-catenin signaling pathway, and subsequently unveiled its integral involvement across a diverse spectrum of signaling cascades. Th...

    Authors: Lu Qiu, Yixuan Sun, Haoming Ning, Guanyu Chen, Wenshan Zhao and Yanfeng Gao
    Citation: Cell Communication and Signaling 2024 22:77
  21. The crosstalk between astrocytes and microglia plays a pivotal role in neuroinflammation following ischemic stroke, and phenotypic distribution of these cells can change with the progression of ischemic stroke...

    Authors: Li Peng, Yanyan Ji, Yixin Li, Yan You and Yang Zhou
    Citation: Cell Communication and Signaling 2024 22:76
  22. Parkinson’s disease (PD), a chronic and severe neurodegenerative disease, is pathologically characterized by the selective loss of nigrostriatal dopaminergic neurons. Dopamine (DA), the neurotransmitter produc...

    Authors: Bing Chen, Qian Zhang, Xiaoru Zhong, Xinwei Zhang, Xin Liu, Hongyang Wang, Fan Yang, Jingjing Zhang, Jingnan Huang, Yin-Kwan Wong, Piao Luo, Jigang Wang and Jichao Sun
    Citation: Cell Communication and Signaling 2024 22:75
  23. The functions of macrophages are governed by distinct polarization phenotypes, which can be categorized as either anti-tumor/M1 type or pro-tumor/M2 type. Glycosylation is known to play a crucial role in vario...

    Authors: Xin He, Bowen Wang, Wenli Deng, Jinhua Cao, Zengqi Tan, Xiang Li and Feng Guan
    Citation: Cell Communication and Signaling 2024 22:73
  24. Over the past decade, the role of the 14–3-3 protein has received increasing interest. Seven subtypes of 14–3-3 proteins exhibit high homology; however, each subtype maintains its specificity. The 14–3-3ε prot...

    Authors: Yue Zhang, Man Yan, Yongjun Yu, Jiangping Wang, Yuqi Jiao, Minying Zheng and Shiwu Zhang
    Citation: Cell Communication and Signaling 2024 22:72
  25. Integrinβ-1 (ITGB1) is a crucial member of the transmembrane glycoprotein signaling receptor family and is also central to the integrin family. It forms heterodimers with other ligands, participates in intrace...

    Authors: Chen Su, Jie Mo, Shuilin Dong, Zhibin Liao, Bixiang Zhang and Peng Zhu
    Citation: Cell Communication and Signaling 2024 22:71
  26. Accumulating evidence indicates that exosomes help to regulate bone homeostasis. The roles of bone-derived exosomes have been well-described; however, recent studies have shown that some non-bone-derived exoso...

    Authors: Ping Wang, Wenkai Shao, Zilin Li, Bo Wang, Xiao Lv, Yiyao Huang and Yong Feng
    Citation: Cell Communication and Signaling 2024 22:70
  27. Tumors of the digestive system pose a significant threat to human health and longevity. These tumors are associated with high morbidity and mortality rates, leading to a heavy economic burden on healthcare sys...

    Authors: Mengjuan Xuan, Xinyu Gu, Yingru Liu, Li Yang, Yi Li, Di Huang, Juan Li and Chen Xue
    Citation: Cell Communication and Signaling 2024 22:69
  28. Digestive tract tumors are heterogeneous and involve the dysregulation of multiple signaling pathways. The Janus kinase-signal transducer and activator of transcription (JAK–STAT) pathway plays a notable role ...

    Authors: Ruihong Zhao, Zhangmin Hu, Xiaoli Zhang, Shujuan Huang, Guodong Yu, Zhe Wu, Wei Yu, Juan Lu and Bing Ruan
    Citation: Cell Communication and Signaling 2024 22:68
  29. Protein Phosphatase 1 (PP1) is a major serine/threonine phosphatase in eukaryotes, participating in several cellular processes and metabolic pathways. Due to their low substrate specificity, PP1’s catalytic su...

    Authors: Pedro O. Corda, Mathieu Bollen, Daniela Ribeiro and Margarida Fardilha
    Citation: Cell Communication and Signaling 2024 22:65
  30. Authors: Alicia Villacampa, Enrique Alfaro, Cristina Morales, Elena Díaz-García, Cristina López-Fernández, José Luis Bartha, Francisco López-Sánchez, Óscar Lorenzo, Salvador Moncada, Carlos F. Sánchez-Ferrer, Francisco García-Río, Carolina Cubillos-Zapata and Concepción Peiró
    Citation: Cell Communication and Signaling 2024 22:64

    The original article was published in Cell Communication and Signaling 2024 22:38

  31. Porcine seminal plasma (SP) is endowed with a heterogeneous population of extracellular vesicles (sEVs). This study evaluated the immunophenotypic profile by high-sensitivity flow cytometry of eight sEV subpop...

    Authors: Isabel Barranco, Alberto Alvarez-Barrientos, Ana Parra, Pablo Martínez-Díaz, Xiomara Lucas and Jordi Roca
    Citation: Cell Communication and Signaling 2024 22:63
  32. Previous research has reported that prenatal exposure to dexamethasone (PDE) results in organ dysplasia and increased disease susceptibility in offspring. This study aimed to investigate the epigenetic mechani...

    Authors: Hao Xiao, Bo He, Heze Liu, Yawen Chen, Di Xiao and Hui Wang
    Citation: Cell Communication and Signaling 2024 22:62
  33. During human early placentation, a proportion of extravillous trophoblasts (EVTs) migrate to the maternal decidua, differentiating into endovascular EVTs to remodel spiral arteries and ensure the establishment...

    Authors: Xiangxin Lan, Ling Guo, Cuiping Hu, Qian Zhang, Jianye Deng, Yufeng Wang, Zi-Jiang Chen, Junhao Yan and Yan Li
    Citation: Cell Communication and Signaling 2024 22:61
  34. Increasing evidence has indicated that long non-coding RNAs (lncRNAs) have been proven to regulate esophageal cancer progression. The lncRNA protein disulfide isomerase family A member 3 pseudogene 1 (PDIA3P1)...

    Authors: Tao Huang, Qi You, Dengjun Huang, Yan Zhang, Zhijie He, Xuguang Shen, Fei Li, Qiang Shen, Ifeanyi Christian Onyebuchi, Chengwei Wu, Feng Liu and Shaojin Zhu
    Citation: Cell Communication and Signaling 2024 22:60
  35. The immune responses to cancer cells involve both innate and acquired immune cells. In the meantime, the most attention has been drawn to the adaptive immune cells, especially T cells, while, it is now well kn...

    Authors: Asal Barshidi, Keivan Ardeshiri, Farbod Ebrahimi, Fatemeh Alian, Ali Akbar Shekarchi, Mohammad Hojjat-Farsangi and Farhad Jadidi-Niaragh
    Citation: Cell Communication and Signaling 2024 22:59
  36. The Ca2+-independent contraction of vascular smooth muscle is a leading cause of cardiovascular and cerebrovascular spasms. In the previous study, we demonstrated the involvement of Src family protein tyrosine ki...

    Authors: Ying Zhang, Nan Li and Sei Kobayashi
    Citation: Cell Communication and Signaling 2024 22:58
  37. The incidence of melanoma is increasing worldwide. Since metastatic melanoma is highly aggressive, it is important to decipher all the biological aspects of melanoma cells. In this context, we have previously ...

    Authors: Jana Karbanová, Ilker A. Deniz, Michaela Wilsch-Bräuninger, Rita Alexandra de Sousa Couto, Christine A. Fargeas, Mark F. Santos, Aurelio Lorico and Denis Corbeil
    Citation: Cell Communication and Signaling 2024 22:57
  38. Colorectal cancer is one of the most common causes of mortality worldwide. There are several potential risk factors responsible for the initiation and progression of colorectal cancer, including age, family hi...

    Authors: Amin Kamrani, Hadi Nasiri, Ali Hassanzadeh, Javad Ahmadian Heris, Reza Mohammadinasab, Shahram Sadeghvand, Mohammadreza Sadeghi, Zahra Valedkarimi, Ramin Hosseinzadeh, Navid Shomali and Morteza Akbari
    Citation: Cell Communication and Signaling 2024 22:56
  39. Breast cancer, a highly fatal disease due to its tendency to metastasize, is the most prevalent form of malignant tumors among women worldwide. Numerous studies indicate that breast cancer exhibits a unique pr...

    Authors: Jingtong Xu, Fangyan Gao, Weici Liu and Xiaoxiang Guan
    Citation: Cell Communication and Signaling 2024 22:55
  40. The gut microbiota plays a crucial role in coronary artery disease (CAD) development, but limited attention has been given to the role of the microbiota in preventing this disease. This study aimed to identify...

    Authors: Hai-Tao Yang, Zhi-hui Jiang, Yi Yang, Ting-Ting Wu, Ying-Ying Zheng, Yi-Tong Ma and Xiang Xie
    Citation: Cell Communication and Signaling 2024 22:54
  41. Ferroptosis is a regulatory cell death process pivotal in myocardial ischemia–reperfusion (I/R) injury. However, the precise mechanism underlying myocardial ferroptosis remains less known. In this study, we in...

    Authors: Junchen Guo, Shanjie Wang, Xin Wan, Xiaoxuan Liu, Zeng Wang, Chenchen Liang, Zhenming Zhang, Ye Wang, Miao Yan, Pengyan Wu, Shaohong Fang and Bo Yu
    Citation: Cell Communication and Signaling 2024 22:53
  42. Neutrophil extracellular traps (NETs) have been implicated in thrombotic diseases. There is no definitive explanation for how NETs form during acute ischemic strokes (AIS). The purpose of our study was to inve...

    Authors: Xin Gao, Xinyi Zhao, Jiacheng Li, Chang Liu, Wenqiang Li, Junjie Zhao, Zhixi Li, Nan Wang, Fang Wang, Jiawei Dong, Xiuwei Yan, Jiheng Zhang, Xueyan Hu, Jiaqi Jin, Ge Mang, Ruishuang Ma…
    Citation: Cell Communication and Signaling 2024 22:50
  43. N4-acetylcytidine (ac4C) is a highly conserved chemical modification widely found in eukaryotic and prokaryotic RNA, such as tRNA, rRNA, and mRNA. This modification is significantly associated with various human ...

    Authors: Shujun Zhang, Yafeng Liu, Xiao Ma, Xiaohui Gao, Yi Ru, Xinjun Hu and Xinyu Gu
    Citation: Cell Communication and Signaling 2024 22:49
  44. Bacterial meningitis remains a leading cause of infection-related mortality worldwide. Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the underlying mechanisms governing b...

    Authors: Ruicheng Yang, Xinyi Wang, Hulin Liu, Jiaqi Chen, Chen Tan, Huanchun Chen and Xiangru Wang
    Citation: Cell Communication and Signaling 2024 22:44
  45. The human CXC chemokine receptor 2 (CXCR2) is a G protein-coupled receptor (GPCR) interacting with multiple chemokines (i.e., CXC chemokine ligands CXCL1-3 and CXCL5-8). It is involved in inflammatory diseases as...

    Authors: Katrijn Boon, Nathan Vanalken, Martyna Szpakowska, Andy Chevigné, Dominique Schols and Tom Van Loy
    Citation: Cell Communication and Signaling 2024 22:43

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