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  1. Several different signaling pathways that regulate cell proliferation and differentiation are initiated by binding of ligands to cell-surface and membrane-bound enzyme-linked receptors, such as receptor tyrosi...

    Authors: Emanuele Murgo, Giorgia Falco, Gaetano Serviddio, Gianluigi Mazzoccoli and Tommaso Colangelo
    Citation: Cell Communication and Signaling 2024 22:319
  2. Alzheimer’s disease is the most common cause of dementia and is characterized by amyloid-β plaques, tau neurofibrillary tangles, and neuronal loss. Although neuronal loss is a primary hallmark of Alzheimer’s d...

    Authors: Tabea M. Soelter, Timothy C. Howton, Amanda D. Clark, Vishal H. Oza and Brittany N. Lasseigne
    Citation: Cell Communication and Signaling 2024 22:317
  3. Authors: Mengqi Gu, Pengzheng Chen, Dongmei Zeng, Xiaotong Jiang, Qingfeng Lv, Yuchen Li, Fengyuan Zhang, Shuting Wan, Qian Zhou, Yuan Lu, Xietong Wang and Lei Li
    Citation: Cell Communication and Signaling 2024 22:316

    The original article was published in Cell Communication and Signaling 2023 21:336

  4. Aberrant inflammatory responses drive the initiation and progression of various diseases, and hyperactivation of NLRP3 inflammasome is a key pathogenetic mechanism. Pharmacological inhibitors of NLRP3 represen...

    Authors: Wenhao Liao, Yuchen Li, Jingwen Liu, Yu Mou, Mei Zhao, Juan Liu, Tianxin Zhang, Qin Sun, Jianyuan Tang and Zhilei Wang
    Citation: Cell Communication and Signaling 2024 22:315
  5. Abnormally expressed BCR/ABL protein serves as the basis for the development of chronic myeloid leukaemia (CML). The F-actin binding domain (FABD), which is a crucial region of the BCR/ABL fusion protein, is a...

    Authors: Renren Zheng, Wei Wei, Suotian Liu, Dachuan Zeng, Zesong Yang, Jie Tang, Jinfeng Tan, Zhenglan Huang and Miao Gao
    Citation: Cell Communication and Signaling 2024 22:314
  6. Non-small-cell lung cancer (NSCLC) accounts for 80–85% of all lung cancer and is the leading cause of cancer-related deaths globally. Although various treatment strategies have been introduced, the 5-year surv...

    Authors: Zhengyan Wu, Min Jiao, Chenying Shu, Saiqun Zhang, Jiajia Wang, Jianhong Pu, Jianjie Zhu, Yuanyuan Zeng, Yehan Zhu and Zeyi Liu
    Citation: Cell Communication and Signaling 2024 22:313
  7. African American (AA) women are twice as likely to develop triple-negative breast cancer (TNBC) as women of European descent. Additionally, AA women with TNBC present a much more aggressive disease course than...

    Authors: Chakravarthy Garlapati, Shriya Joshi, Chunhua Yang, Darshan Shimoga Chandrashekar, Padmashree Rida and Ritu Aneja
    Citation: Cell Communication and Signaling 2024 22:312
  8. Neuroinflammation is widely acknowledged as a characteristic feature of almost all neurological disorders and specifically in depression- and anxiety-like disorders. In recent years, there has been significant...

    Authors: Daiki Wakasugi, Shinji Kondo, Farhana Ferdousi, Seiya Mizuno, Akira Yada, Kenichi Tominaga, Satoru Takahashi and Hiroko Isoda
    Citation: Cell Communication and Signaling 2024 22:309
  9. Gasdermin D (GSDMD) is emerging as an important player in autoimmune diseases, but its exact role in lupus nephritis (LN) remains controversial. Here, we identified markedly elevated GSDMD in human and mouse L...

    Authors: Jiani Shen, Feng Li, Xu Han, Dongying Fu, Yiping Xu, Changjian Zhu, Zhou Liang, Ziwen Tang, Ruilin Zheng, Xinrong Hu, Ruoni Lin, Qiaoqiao Pei, Jing Nie, Ning Luo, Xiaoyan Li, Wei Chen…
    Citation: Cell Communication and Signaling 2024 22:308
  10. Interleukin 24 (IL-24) has been implicated in the nociceptive signaling. However, direct evidence and the precise molecular mechanism underlying IL-24’s role in peripheral nociception remain unclear.

    Authors: Hua Cai, Siyu Chen, Yufang Sun, Tingting Zheng, Yulu Liu, Jin Tao and Yuan Zhang
    Citation: Cell Communication and Signaling 2024 22:307
  11. Dysregulation in histone acetylation, a significant epigenetic alteration closely associated with major pathologies including cancer, promotes tumorigenesis, inactivating tumor-suppressor genes and activating ...

    Authors: Botao Pan, Can Liu, Jiyan Su and Chenglai Xia
    Citation: Cell Communication and Signaling 2024 22:306

    The Correction to this article has been published in Cell Communication and Signaling 2024 22:327

  12. As a major component of innate immunity and a positive regulator of interferons, the Stimulator of interferon gene (STING) has an immunotherapy potential to govern a variety of infectious diseases. Despite the...

    Authors: Aysa Rezabakhsh, M. Reza Sadaie, Alireza Ala, Yousef Roosta, Solomon Habtemariam, Adeleh Sahebnasagh and Mohammad Rafi Khezri
    Citation: Cell Communication and Signaling 2024 22:305
  13. Elevated concentrations of palmitate in serum of obese individuals can impair endothelial function, contributing to development of cardiovascular disease. Although several molecular mechanisms of palmitate-ind...

    Authors: Igor Kovacevic, Paula Henriette Schmidt, Annkatrin Kowalski, Bernd J. Helms, Chris H. A. van de Lest, Alexander Kluttig and Guido Posern
    Citation: Cell Communication and Signaling 2024 22:304
  14. While previous studies have primarily focused on Glucose transporter type 1 (GLUT1) related glucose metabolism signaling, we aim to discover if GLUT1 promotes tumor progression through a non-metabolic pathway.

    Authors: Zhiqing Zhou, Yu Li, Sijie Chen, Zhangrong Xie, Yuhui Du, Yue Liu, Yuxuan Shi, Xiangyi Lin, Xiaofei Zeng, Huijie Zhao and Guoan Chen
    Citation: Cell Communication and Signaling 2024 22:303
  15. The ubiquitination-mediated protein degradation exerts a vital role in the progression of multiple tumors. NEDD4L, which belongs to the E3 ubiquitin ligase NEDD4 family, is related to tumor genesis, metastasis...

    Authors: Yijun Shi, Na Fang, Yutong Wu, Huiwen Xu, Anhui Ning, Wendi Zhang, Yiran Liu, Xiaobo Tao, Qiong Chen, Tian Tian, Lei Zhang, Minjie Chu and Jiahua Cui
    Citation: Cell Communication and Signaling 2024 22:302
  16. Intrauterine adhesion (IUA) is one of the most severe causes of infertility in women of childbearing age with injured endometrium secondary to uterine performance. Stem cell therapy is effective in treating da...

    Authors: Xiyue Huang, Xiao Yang, Jinglin Huang, Ling Wei, Yanhua Mao, Changjiang Li, Yingfeng Zhang, Qiuhong Chen, Shasha Wu, Lele Xie, Congcong Sun, Wenwen Zhang and Jia Wang
    Citation: Cell Communication and Signaling 2024 22:301

    The Correction to this article has been published in Cell Communication and Signaling 2024 22:326

  17. Optimizing the efficiency of definitive endoderm (DE) differentiation is necessary for the generation of diverse organ-like structures. In this study, we used the small molecule inhibitor saracatinib (SAR) to ...

    Authors: Ruiyang Ma, Huanjing Bi, Ying Wang, Jingwen Wang, Jiangwei Zhang, Xiaoyang Yu, Zuhan Chen, Jiale Wang, Cuinan Lu, Jin Zheng, Yang Li and Xiaoming Ding
    Citation: Cell Communication and Signaling 2024 22:300
  18. Eph receptors constitute the largest family of receptor tyrosine kinases, comprising 14 distinct members classified into two subgroups: EphAs and EphBs.. Despite their essential functions in normal physiologic...

    Authors: Xiaoting Guo, Yanyi Yang, Jingqun Tang and Juanjuan Xiang
    Citation: Cell Communication and Signaling 2024 22:299
  19. Nucleobindin-2 (Nucb2) and nesfatin-1 (N1) are widely distributed hormones that regulate numerous physiological processes, from energy homeostasis to carcinogenesis. However, the role of nesfatin-2 (N2), the s...

    Authors: Rafał Lenda, Lilia Zhukova, Andrzej Ożyhar and Dominika Bystranowska
    Citation: Cell Communication and Signaling 2024 22:298
  20. Endoplasmic reticulum (ER) stress-mediated increases in the hepatic levels of the very low-density lipoprotein (VLDL) receptor (VLDLR) promote hepatic steatosis by increasing the delivery of triglyceride-rich ...

    Authors: Mona Peyman, Anna Babin-Ebell, Rosalía Rodríguez-Rodríguez, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Francesc Villarroya, Xavier Palomer, Emma Barroso and Manuel Vázquez-Carrera
    Citation: Cell Communication and Signaling 2024 22:297
  21. The SARS-CoV-2 virus causes severe COVID-19 in one-fifth of patients. In addition to high mortality, infection may induce respiratory failure and cardiovascular complications associated with inflammation. Acut...

    Authors: Wojciech M. Ciszewski, Lucyna A. Woźniak and Katarzyna Sobierajska
    Citation: Cell Communication and Signaling 2024 22:296
  22. Colorectal cancer (CRC) commonly exhibits tolerance to cisplatin treatment, but the underlying mechanisms remain unclear. Within the tumor microenvironment, macrophages play a role in resisting the cytotoxic e...

    Authors: Zhixin Ma, Yu Sun, Yang Yu, Wenjun Xiao, Zhijie Xiao, Tianyu Zhong, Xi Xiang and Zhigang Li
    Citation: Cell Communication and Signaling 2024 22:295
  23. Acute respiratory distress syndrome (ARDS) is a severe and fatal disease. Although mesenchymal stem cell (MSC)-based therapy has shown remarkable efficacy in treating ARDS in animal experiments, clinical outco...

    Authors: Xiao Wu, Ying Tang, Xinxing Lu, Yigao Liu, Xu Liu, Qin Sun, Lu Wang, Wei Huang, Airan Liu, Ling Liu, Jie Chao, Xiwen Zhang and Haibo Qiu
    Citation: Cell Communication and Signaling 2024 22:293
  24. Hematopoietic stem cell (HSC) regeneration underlies hematopoietic recovery from myelosuppression, which is a life-threatening side effect of cytotoxicity. HSC niche is profoundly disrupted after myelosuppress...

    Authors: Weinian Liao, Xinliang Chen, Shuzhen Zhang, Jun Chen, Chaonan Liu, Kuan Yu, Yimin Zhang, Mo Chen, Fang Chen, Mingqiang Shen, Binghui Lu, Songling Han, Song Wang, Junping Wang and Changhong Du
    Citation: Cell Communication and Signaling 2024 22:292
  25. A promising new therapy option for acute kidney injury (AKI) is mesenchymal stem cells (MSCs). However, there are several limitations to the use of MSCs, such as low rates of survival, limited homing capacity,...

    Authors: Yifan Zhang, Xiaochen Wang, Yuwei Ji, Haijuan Hong, Xiaodong Geng, Keying Zhang, Zhangning Fu, Guangyan Cai, Xiangmei Chen, Ping Li and Quan Hong
    Citation: Cell Communication and Signaling 2024 22:291
  26. The Crumbs protein (CRB) family plays a crucial role in maintaining the apical–basal polarity and integrity of embryonic epithelia. The family comprises different isoforms in different animals and possesses di...

    Authors: Xuebin Zhou, Liangliang Zhao, Chenguang Wang, Wei Sun, Bo Jia, Dan Li and Jinling Fu
    Citation: Cell Communication and Signaling 2024 22:290
  27. A cell is a dynamic system in which various processes occur simultaneously. In particular, intra- and intercellular signaling pathway crosstalk has a significant impact on a cell’s life cycle, differentiation,...

    Authors: I. A. Govorova, S. Y. Nikitochkina and E. A. Vorotelyak
    Citation: Cell Communication and Signaling 2024 22:289
  28. Chronic wounds, resulting from persistent inflammation, can trigger a cascade of detrimental effects including exacerbating inflammatory cytokines, compromised blood circulation at the wound site, elevation of...

    Authors: Xingrui Mu, Rifang Gu, Ming Tang, Xingqian Wu, Wenjie He and Xuqiang Nie
    Citation: Cell Communication and Signaling 2024 22:288
  29. Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal types of cancer, and KRAS oncogene occurs in over 90% of cases. P21-activated kinases (PAK), containing six members (PAK1 to 6), function downstrea...

    Authors: Yi Ma, Chelsea Dumesny, Li Dong, Ching-Seng Ang, Khashayar Asadi, Yifan Zhan, Mehrdad Nikfarjam and Hong He
    Citation: Cell Communication and Signaling 2024 22:287
  30. T-cell membrane scaffold proteins are pivotal in T cell function, acting as versatile signaling hubs. While CD6 forms a large intracellular signalosome, it is distinguished from typical scaffolds like LAT or P...

    Authors: Rita F. Santos, Annika de Sousa Linhares, Peter Steinberger, Simon. J. Davis, Liliana Oliveira and Alexandre M. Carmo
    Citation: Cell Communication and Signaling 2024 22:286
  31. Aging is a complex and multifaceted process involving a variety of interrelated molecular mechanisms and cellular systems. Phenotypically, the biological aging process is accompanied by a gradual loss of cellu...

    Authors: Yumeng Li, Xutong Tian, Juyue Luo, Tongtong Bao, Shujin Wang and Xin Wu
    Citation: Cell Communication and Signaling 2024 22:285
  32. To elucidate the mechanism of dysfunction of tolerogenic dendritic cells (DCs) is of significance. Telomerase involves the regulation of the cell fate and activities. The objective of this study is to investig...

    Authors: Xuejie Xu, Lihua Mo, Yun Liao, Kaitlyn Song Zhang, Hanqing Zhang, Le Liu, Yu Liu, Aifa Tang, Pingchang Yang and Xiaoyu Liu
    Citation: Cell Communication and Signaling 2024 22:284
  33. In addition to functioning as a precise monitoring mechanism in cell cycle, the anaphase-promoting complex/cyclosome (APC/C) is reported to be involved in regulating multiple metabolic processes by facilitatin...

    Authors: Huihui Zhao, Xinxin Cheng, Liping Yan, Fang Mi, Wenqing Wang, Yuying Hu, Xingyang Liu, Yuyan Fan, Qingjie Min, Yan Wang, Weimin Zhang, Qingnan Wu and Qimin Zhan
    Citation: Cell Communication and Signaling 2024 22:283
  34. Extracellular vesicles (EVs) constitute a vital component of intercellular communication, exerting significant influence on metastasis formation and drug resistance mechanisms. Malignant melanoma (MM) is one o...

    Authors: Afrodité Németh, Gréta L. Bányai, Nikolett K. Dobos, Tamás Kós, Anikó Gaál, Zoltán Varga, Edit I. Buzás, Delaram Khamari, Magdolna Dank, István Takács, A. Marcell Szász and Tamás Garay
    Citation: Cell Communication and Signaling 2024 22:282
  35. Restoring impaired peripheral immune tolerance is the primary challenge in treating autoimmune diseases. Our previous research demonstrated the effectiveness of small spleen peptides (SSPs), a fraction of low ...

    Authors: Viktor Wixler, Yvonne Boergeling, Rafael Leite Dantas, Georg Varga and Stephan Ludwig
    Citation: Cell Communication and Signaling 2024 22:281
  36. Hepatitis B Virus (HBV) is widely recognized as a “metabolic virus” that disrupts hepatic metabolic homeostasis, rendering it one of the foremost risk factors for hepatocellular carcinoma (HCC). Except for ant...

    Authors: Ying Zhu, Yingke Zhao, Zhouyu Ning, Yong Deng, Bing Li, Yun Sun and Zhiqiang Meng
    Citation: Cell Communication and Signaling 2024 22:280
  37. O-linked N-acetylglucosamine (O-GlcNAc) protein modification (O-GlcNAcylation) is a critical post-translational modification (PTM) of cytoplasmic and nuclear proteins. O-GlcNAcylation levels are regulated by t...

    Authors: Xiaohan Yan, Jingjing Zheng, Wenhao Ren, Shaoming Li, Shuying Yang, Keqian Zhi and Ling Gao
    Citation: Cell Communication and Signaling 2024 22:279
  38. While de novo cholesterol biosynthesis plays a crucial role in chemotherapy resistance of colorectal cancer (CRC), the underlying molecular mechanism remains poorly understood.

    Authors: Qi Liu, Yajuan Zhang, Huimin Li, Hong Gao, Yijie Zhou, Dakui Luo, Zezhi Shan, Yufei Yang, Junyong Weng, Qingguo Li, Weiwei Yang and Xinxiang Li
    Citation: Cell Communication and Signaling 2024 22:278
  39. Bcl-2 and Bcl-xL are the most studied anti-apoptotic members of Bcl-2 family proteins. We previously characterized both of them, not only for their role in regulating apoptosis and resistance to therapy in can...

    Authors: Simona D’Aguanno, Matteo Brignone, Stefano Scalera, Martina Chiacchiarini, Marta Di Martile, Elisabetta Valentini, Francesca De Nicola, Alessia Ricci, Fabio Pelle, Claudio Botti, Marcello Maugeri-Saccà and Donatella Del Bufalo
    Citation: Cell Communication and Signaling 2024 22:277
  40. Traditionally, lactate has been considered a ‘waste product’ of cellular metabolism. Recent findings have shown that lactate is a substance that plays an indispensable role in various physiological cellular fu...

    Authors: Yunda Fang, Zhengjun Li, Lili Yang, Wen Li, Yutong Wang, Ziyang Kong, Jia Miao, Yanqi Chen, Yaoyao Bian and Li Zeng
    Citation: Cell Communication and Signaling 2024 22:276
  41. Diabetic retinopathy (DR) is a major cause of blindness and is characterized by dysfunction of the retinal microvasculature. Neutrophil stasis, resulting in retinal inflammation and the occlusion of retinal mi...

    Authors: Ting Li, Yixia Qian, Haicheng Li, Tongtong Wang, Qi Jiang, Yuchan Wang, Yanhua Zhu, Shasha Li, Xuemin He, Guojun Shi, Wenru Su, Yan Lu and Yanming Chen
    Citation: Cell Communication and Signaling 2024 22:275
  42. Extracellular ATP–AMP–adenosine metabolism plays a pivotal role in modulating tumor immune responses. Previous studies have shown that the conversion of ATP to AMP is primarily catalysed by Ectonucleoside trip...

    Authors: Mengchen Shi, Linsen Ye, Lu Zhao, Lingyuan He, Junxiong Chen, Jingdan Zhang, Yixi Su, Haiyan Dong, Jiaqi Liu, Liumei Liang, Wenwen Zheng, Yanhong Xiao, Huanliang Liu, Xiangling Yang and Zihuan Yang
    Citation: Cell Communication and Signaling 2024 22:274
  43. Small extracellular vesicles (sEVs) are important mediators of intercellular communication by transferring of functional components (proteins, RNAs, and lipids) to recipient cells. Some PTMs, including phospho...

    Authors: Xiulan Chen, Xi Song, Jiaran Li, Jifeng Wang, Yumeng Yan and Fuquan Yang
    Citation: Cell Communication and Signaling 2024 22:273
  44. In the tumor immune microenvironment (TIME), triggering receptor expressed on myeloid cells 2 (trem2) is widely considered to be a crucial molecule on tumor-associated macrophages(TAMs). Multiple studies have ...

    Authors: Yunji Yan, Shengwei Bai, Hongxi Han, Junqiang Dai, Liang Niu, Hongyu Wang, Qiang Dong, Hang Yin, Guoqiang Yuan and Yawen Pan
    Citation: Cell Communication and Signaling 2024 22:272
  45. Macrophages are key inflammatory immune cells that orchestrate the initiation and progression of autoimmune diseases. The characters of macrophage in diseases are determined by its phenotype in response to the...

    Authors: Li-Wen Zhu, Zihao Li, Xiaohong Dong, Huadong Wu, Yifan Cheng, Shengnan Xia, Xinyu Bao, Yun Xu and Runjing Cao
    Citation: Cell Communication and Signaling 2024 22:271
  46. Fibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular ligands, fibroblast growth factors (FGFs), initiates an i...

    Authors: Dominika Żukowska, Aleksandra Chorążewska, Krzysztof Ciura, Aleksandra Gędaj, Marta Kalka, Marta Poźniak, Natalia Porębska and Łukasz Opaliński
    Citation: Cell Communication and Signaling 2024 22:270
  47. Low sperm motility is a significant contributor to male infertility. beta-defensins have been implicated in host defence and the acquisition of sperm motility; however, the regulatory mechanisms governing thei...

    Authors: Guoliang Zhang, Yuanchao Sun, Minkai Guan, Mengmeng Liu and Shiduo Sun
    Citation: Cell Communication and Signaling 2024 22:267

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  • Citation Impact 2023
    Journal Impact Factor: 8.2
    5-year Journal Impact Factor: 8.0
    Source Normalized Impact per Paper (SNIP): 1.569
    SCImago Journal Rank (SJR): 2.308

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    Submission to first editorial decision (median days): 5
    Submission to acceptance (median days): 83

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