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  1. Tubulointerstitial kidney disease associated microenvironmental dysregulation, like acidification, inflammation and fibrosis, affects tubule cells and fibroblasts. Micromilieu homeostasis influences intracellu...

    Authors: Marie-Christin Schulz, Michael Kopf and Michael Gekle
    Citation: Cell Communication and Signaling 2024 22:148
  2. Patients with Alzheimer’s disease (AD) are often co-morbid with unprovoked seizures, making clinical diagnosis and management difficult. Although it has an important role in both AD and epilepsy, abnormal γ-am...

    Authors: Rui Mao, Mengsha Hu, Xuan Liu, Lei Ye, Bingsong Xu, Min Sun, Siyi Xu, Wenxuan Shao, Yi Tan, Yun Xu, Feng Bai and Shu Shu
    Citation: Cell Communication and Signaling 2024 22:147
  3. Paraquat (PQ) is an irreplaceable insecticide in many countries for the advantage of fast-acting and broad-spectrum. However, PQ was classified as the most prevailing poisoning substance for suicide with no sp...

    Authors: Jing Du, Lingyan Yu, Xinyi Yang, Fangchun Shao, Jun Xia, Weidong Jin, Yinhao Zhang, Guojie Lei, Ying Wang, Yanchun Li and Jun Zhang
    Citation: Cell Communication and Signaling 2024 22:146
  4. ZEB1, a core transcription factor involved in epithelial-mesenchymal transition (EMT), is associated with aggressive cancer cell behavior, treatment resistance, and poor prognosis across various tumor types. S...

    Authors: Samlai Vedovatto, Fernanda Dittrich Oliveira, Luiza Cherobini Pereira, Thamiris Becker Scheffel, Liziane Raquel Beckenkamp, Ana Paula Santin Bertoni, Márcia Rosângela Wink and Guido Lenz
    Citation: Cell Communication and Signaling 2024 22:145
  5. Solid tumors such as glioblastoma (GBM) exhibit hypoxic zones that are associated with poor prognosis and immunosuppression through multiple cell intrinsic mechanisms. However, release of extracellular vesicle...

    Authors: Stoyan Tankov, Marija Petrovic, Marc Lecoultre, Felipe Espinoza, Nadia El-Harane, Viviane Bes, Sylvie Chliate, Darel Martinez Bedoya, Olivier Jordan, Gerrit Borchard, Denis Migliorini, Valérie Dutoit and Paul R. Walker
    Citation: Cell Communication and Signaling 2024 22:144
  6. Calcium is a ubiquitous intracellular messenger that regulates the expression of various genes involved in cell proliferation, differentiation, and motility. The involvement of calcium in diverse metabolic pat...

    Authors: Laxman Manandhar, Raghbendra Kumar Dutta, Pradeep Devkota, Arun Chhetri, Xiaofan Wei, Channy Park, Hyug Moo Kwon and Raekil Park
    Citation: Cell Communication and Signaling 2024 22:142
  7. Lipids are regulators of insulitis and β-cell death in type 1 diabetes development, but the underlying mechanisms are poorly understood. Here, we investigated how the islet lipid composition and downstream sig...

    Authors: Soumyadeep Sarkar, Cailin Deiter, Jennifer E. Kyle, Michelle A. Guney, Dylan Sarbaugh, Ruichuan Yin, Xiangtang Li, Yi Cui, Mireia Ramos-Rodriguez, Carrie D. Nicora, Farooq Syed, Jonas Juan-Mateu, Charanya Muralidharan, Lorenzo Pasquali, Carmella Evans-Molina, Decio L. Eizirik…
    Citation: Cell Communication and Signaling 2024 22:141
  8. Hostile microenvironment of cancer cells provoke a stressful condition for endoplasmic reticulum (ER) and stimulate the expression and secretion of ER chaperones, leading to tumorigenic effects. However, the m...

    Authors: Jie Jia, Lianhui Zhu, Xihua Yue, Shuocheng Tang, Shuaiyang Jing, Chuanting Tan, Yulei Du, Jingkai Gao, Intaek Lee and Yi Qian
    Citation: Cell Communication and Signaling 2024 22:140
  9. Malaria remains a global health burden, and the emergence and increasing spread of drug resistance to current antimalarials poses a major challenge to malaria control. There is an urgent need to find new drugs...

    Authors: Peng Gao, Jianyou Wang, Huan Tang, Huanhuan Pang, Jiemei Liu, Chen Wang, Fei Xia, Honglin Chen, Liting Xu, Junzhe Zhang, Lixia Yuan, Guang Han, Jigang Wang and Gang Liu
    Citation: Cell Communication and Signaling 2024 22:139
  10. Applications of nonthermal plasma have expanded beyond the biomedical field to include antibacterial, anti-inflammatory, wound healing, and tissue regeneration. Plasma enhances epithelial cell repair; however,...

    Authors: Sung Un Kang, Haeng Jun Kim, Sukhwal Ma, Doo-Yi Oh, Jeon Yeob Jang, Chorong Seo, Yun Sang Lee and Chul-Ho Kim
    Citation: Cell Communication and Signaling 2024 22:138
  11. Protein phosphorylation is one of the most prevalent posttranslational modifications involved in molecular control of cellular processes, and is mediated by over 520 protein kinases in humans and other mammals...

    Authors: Brian G. Poll, Kirby T. Leo, Venky Deshpande, Nipun Jayatissa, Trairak Pisitkun, Euijung Park, Chin-Rang Yang, Viswanathan Raghuram and Mark A. Knepper
    Citation: Cell Communication and Signaling 2024 22:137
  12. Diabetic kidney disease (DKD) is a long-term and serious complication of diabetes that affects millions of people worldwide. It is characterized by proteinuria, glomerular damage, and renal fibrosis, leading t...

    Authors: Shiwan Hu, Xing Hang, Yu Wei, Han Wang, Lili Zhang and Linhua Zhao
    Citation: Cell Communication and Signaling 2024 22:136
  13. Ovarian stimulation (OS) during assisted reproductive technology (ART) appears to be an independent factor influencing the risk of low birth weight (LBW). Previous studies identified the association between LB...

    Authors: Xueyan Lu, Jiaqin Mao, Chenxi Qian, Hui Lei, Fei Mu, Huijun Sun, Song Yan, Zheng Fang, Jie Lu, Qian Xu, Jie Dong, Danjie Su, Jingjing Wang, Ni Jin, Shuqiang Chen and Xiaohong Wang
    Citation: Cell Communication and Signaling 2024 22:135
  14. Pancreatic ductal adenocarcinoma is an aggressive cancer type with one of the lowest survival rates due to late diagnosis and the absence of effective treatments. A better understanding of PDAC biology will he...

    Authors: Sandy Anania, Martin Farnir, Raphaël Peiffer, Yasmine Boumahd, Marc Thiry, Ferman Agirman, Naima Maloujahmoum, Akeila Bellahcène and Olivier Peulen
    Citation: Cell Communication and Signaling 2024 22:133
  15. Abnormal inflammatory states in the brain are associated with a variety of brain diseases. The dynamic changes in the number and function of immune cells in cerebrospinal fluid (CSF) are advantageous for the e...

    Authors: Xiaotong Xu, Yi Han, Binlong Zhang, Quanzhong Ren, Juan Ma and Sijin Liu
    Citation: Cell Communication and Signaling 2024 22:132
  16. Malignant tumours seriously threaten human life and health, and effective treatments for cancer are still being explored. The ability of SHC SH2 domain-binding protein 1 (SHCBP1) to induce cell cycle disturban...

    Authors: Mei Zhou, Limin Duan, Jiangbin Chen, Yumei Li, Zhengrong Yin, Siwei Song, Yaqi Cao, Ping Luo, Fan Hu, Guanghai Yang, Juanjuan Xu, Tingting Liao and Yang Jin
    Citation: Cell Communication and Signaling 2024 22:131
  17. In recent decades, emerging data have highlighted the critical role of extracellular vesicles (EVs), especially (exosomes) Exos, in the progression and development of several cancer types. These nano-sized ves...

    Authors: Zahra Abbasi-Malati, Seyed Ghader Azizi, Soheil Zamen Milani, Zeinab Aliyari Serej, Narges Mardi, Zahra Amiri, Zohreh Sanaat and Reza Rahbarghazi
    Citation: Cell Communication and Signaling 2024 22:130
  18. Extracellular vesicles (EVs), including microvesicles, hold promise for the management of bladder urothelial carcinoma (BLCA), particularly because of their utility in identifying therapeutic targets and their...

    Authors: Vijay Kumar Boddu, Piet Zamzow, Mario Wolfgang Kramer, Axel S. Merseburger, Sivahari Prasad Gorantla, Matthias Klinger, Lena Cramer, Thorben Sauer, Timo Gemoll, Nikolas von Bubnoff, Frank Gieseler and Masoud Darabi
    Citation: Cell Communication and Signaling 2024 22:129
  19. In pathologies including cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are underway to target this pathw...

    Authors: Alex S. Choi, Laura M. Jenkins-Lane, Wade Barton, Asha Kumari, Carly Lancaster, Calen Raulerson, Hao Ji, Diego Altomare, Mark D. Starr, Regina Whitaker, Rebecca Phaeton, Rebecca Arend, Michael Shtutman, Andrew B. Nixon, Nadine Hempel, Nam Y. Lee…
    Citation: Cell Communication and Signaling 2024 22:128
  20. All-trans retinoic acid (ATRA) is the most relevant and functionally active metabolite of Vitamin-A. From a therapeutic standpoint, ATRA is the first example of pharmacological agent exerting its anti-tumor acti...

    Authors: Maria Azzurra Caricasulo, Adriana Zanetti, Mineko Terao, Enrico Garattini and Gabriela Paroni
    Citation: Cell Communication and Signaling 2024 22:127
  21. Extensive research in countries with high sociodemographic indices (SDIs) to date has shown that coronavirus disease 2019 (COVID-19) may be directly associated with more severe outcomes among patients living w...

    Authors: Sareh Kakavandi, Bahareh Hajikhani, Paniz Azizi, Fatemeh Aziziyan, Mohsen Nabi-Afjadi, Marzieh Ramezani Farani, Hamidreza Zalpoor, Maryam Azarian, Mahdiyar Iravani Saadi, Behrouz Gharesi-Fard, Evangelos Terpos, Iman Zare and Mohammad Motamedifar
    Citation: Cell Communication and Signaling 2024 22:126
  22. The activation of peroxisome proliferator-activated receptor (PPAR)-γ has been extensively shown to attenuate inflammatory responses in conditions such as asthma, acute lung injury, and acute respiratory distr...

    Authors: I-Ta Lee, Chien-Chung Yang and Chuen-Mao Yang
    Citation: Cell Communication and Signaling 2024 22:125
  23. Autophagy is a self-renewal mechanism that maintains homeostasis and can promote tissue regeneration by regulating inflammation, reducing oxidative stress and promoting cell differentiation. The interaction be...

    Authors: Yan Wu, Luxin Li, Zuojun Ning, Changrong Li, Yongkui Yin, Kaiyuan Chen, Lu Li, Fei Xu and Jie Gao
    Citation: Cell Communication and Signaling 2024 22:124
  24. Meningitic Escherichia coli (E. coli) is the major etiological agent of bacterial meningitis, a life-threatening infectious disease with severe neurological sequelae and high mortality. The major cause of central...

    Authors: Jinrui Sun, Ruicheng Yang, Jiyang Fu, Dong Huo, Xinyi Qu, Chen Tan, Huanchun Chen and Xiangru Wang
    Citation: Cell Communication and Signaling 2024 22:123
  25. Cells that are exposed to harmful genetic damage, either from internal or external sources, may undergo senescence if they are unable to repair their DNA. Senescence, characterized by a state of irreversible g...

    Authors: Nicola Alessio, Domenico Aprile, Gianfranco Peluso, Valeria Mazzone, Deanira Patrone, Giovanni Di Bernardo and Umberto Galderisi
    Citation: Cell Communication and Signaling 2024 22:122
  26. To explore whether the gap junction (GJ) composed by connexin32(Cx32) mediated pyroptosis in renal ischemia-reperfusion(I/R) injury via transmitting miR155-3p, with aim to provide new strategies for the preven...

    Authors: Liubing Chen, Hongyi Fang, Xiaoyun Li, Peiling Yu, Yu Guan, Cuicui Xiao, Zhizhao Deng, Ziqing Hei, Chaojin Chen and Chenfang Luo
    Citation: Cell Communication and Signaling 2024 22:121
  27. Breast cancer (BC) is the most frequent tumor entity in women worldwide with a high chance of therapeutic response in early- and non-metastatic disease stages. Among all BC subtypes, triple-negative BC (TNBC) ...

    Authors: Evangelos Prokakis, Husam Bamahmoud, Shaishavi Jansari, Lena Fritsche, Alexander Dietz, Angela Boshnakovska, Peter Rehling, Steven A. Johnsen, Julia Gallwas and Florian Wegwitz
    Citation: Cell Communication and Signaling 2024 22:120
  28. Breast cancer cells (BCCs) can remain undetected for decades in dormancy. These quiescent cells are similar to cancer stem cells (CSCs); hence their ability to initiate tertiary metastasis. Dormancy can be reg...

    Authors: Alejandra I. Ferrer-Diaz, Garima Sinha, Andrew Petryna, Ruth Gonzalez-Bermejo, Yannick Kenfack, Oluwadamilola Adetayo, Shyam A. Patel, Anupama Hooda-Nehra and Pranela Rameshwar
    Citation: Cell Communication and Signaling 2024 22:119
  29. Disruption of Ca2+ homeostasis after calcium electroporation (CaEP) in tumors has been shown to elicit an enhanced antitumor effect with varying impacts on healthy tissue, such as endothelium. Therefore, our stud...

    Authors: Barbara Lisec, Tim Bozic, Iva Santek, Bostjan Markelc, Milka Vrecl, Robert Frangez and Maja Cemazar
    Citation: Cell Communication and Signaling 2024 22:118
  30. Post-translational modifications (PTMs) of the non-histone protein high-mobility group protein B1 (HMGB1) are involved in modulating inflammation and immune responses. Recent studies have implicated that the R...

    Authors: Xiaole Meng, Risi Na, Xiao Peng, Hui Li, Wanxin Ouyang, Wenting Zhou, Xuting You, Yuhuan Li, Xin Pu, Ke Zhang, Junjie Xia, Jie Wang, Huamei Tang, Guohong Zhuang and Zhihai Peng
    Citation: Cell Communication and Signaling 2024 22:117
  31. R140Q mutation in isocitrate dehydrogenase 2 (IDH2) promotes leukemogenesis. Targeting IDH2/R140Q yields encouraging therapeutic effects in the clinical setting. However, therapeutic resistance occurs in 12% o...

    Authors: Jie Yang, Jiao Chen, Jingjie Chang, Xiaoyan Sun, Qingyun Wei, Xueting Cai and Peng Cao
    Citation: Cell Communication and Signaling 2024 22:116
  32. Phosphorylation proteomics is the basis for the study of abnormally activated kinase signaling pathways in breast cancer, which facilitates the discovery of new oncogenic agents and drives the discovery of pot...

    Authors: Yujiao Deng, Zhanwu Hou, Yizhen Li, Ming Yi, Ying Wu, Yi Zheng, Fei Yang, Guansheng Zhong, Qian Hao, Zhen Zhai, Meng Wang, Xiaobin Ma, Huafeng Kang, Fanpu Ji, Chenfang Dong, Huadong Liu…
    Citation: Cell Communication and Signaling 2024 22:115
  33. Sirtuins, which are NAD+-dependent class III histone deacetylases, are involved in various biological processes, including DNA damage repair, immune inflammation, oxidative stress, mitochondrial homeostasis, auto...

    Authors: Qi Jin, Fang Ma, Tongtong Liu, Liping Yang, Huimin Mao, Yuyang Wang, Liang Peng, Ping Li and Yongli Zhan
    Citation: Cell Communication and Signaling 2024 22:114
  34. Chronic kidney disease (CKD) has historically been a significant global health concern, profoundly impacting both life and well-being. In the process of CKD, with the gradual loss of renal function, the incide...

    Authors: Shiyang Li, Qiuxia Han, Chang Liu, Yixue Wang, Fengxun Liu, Shaokang Pan, Lihua Zuo, Dan Gao, Kai Chen, Qi Feng, Zhangsuo Liu and Dongwei Liu
    Citation: Cell Communication and Signaling 2024 22:113
  35. Though (1S, 3R)-RSL3 has been used widely in basic research as a small molecular inducer of ferroptosis, the toxicity on normal cells and poor pharmacokinetic properties of RSL3 limited its clinical applicatio...

    Authors: Shengjie Peng, Guodong Chen, K. N. Yu, Yue Feng, Lele Zhao, Miaomiao Yang, Wei Cao, Waleed Abdelbagi Ahmed Almahi, Mingyu Sun, Yuan Xu, Ye Zhao, Cheng Cheng, Fengqin Zhu and Wei Han
    Citation: Cell Communication and Signaling 2024 22:112
  36. Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer treatment strategies are evolving due to innate and acquired resistance capacity, governed by genetic, epigenetic, proteomic, m...

    Authors: Sameer Ullah Khan, Kaneez Fatima, Shariqa Aisha and Fayaz Malik
    Citation: Cell Communication and Signaling 2024 22:109
  37. Psoriasis is an immune-mediated inflammatory skin disease, involving a complex interplay between genetic and environmental factors. Previous studies have demonstrated that genetic factors play a major role in ...

    Authors: Suwen Liu, Mengwen He, Jian Jiang, Xiaoru Duan, Bao Chai, Jingyu Zhang, Qingxiao Tao and Hongxiang Chen
    Citation: Cell Communication and Signaling 2024 22:108
  38. Cervical cancer (CC) is a common gynecologic malignancy, accounting for a significant proportion of women death worldwide. Human papillomavirus (HPV) infection is one of the major etiological causes leading to...

    Authors: Emad Heydarnia, Zahra Dorostgou, Neda Hedayati, Vahide Mousavi, Sheida Yahyazadeh, Mina Alimohammadi, Mobina Gheibi, Parasta Heidari, Somayeh Igder, Alireza Mafi and Omid Vakili
    Citation: Cell Communication and Signaling 2024 22:107
  39. Aquaporins (AQPs) are ubiquitous channel proteins that play a critical role in the homeostasis of the cellular environment by allowing the transit of water, chemicals, and ions. They can be found in many diffe...

    Authors: Arkadyuti Bhattacharjee, Ankit Jana, Swagato Bhattacharjee, Sankalan Mitra, Swagata De, Badrah S. Alghamdi, Mohammad Zubair Alam, Ahmad Bakur Mahmoud, Zainab Al Shareef, Wael M. Abdel-Rahman, Chan Woon-Khiong, Athanasios Alexiou, Marios Papadakis and Ghulam Md Ashraf
    Citation: Cell Communication and Signaling 2024 22:106
  40. The current scientific literature has extensively explored the potential role of proteasome inhibitors (PIs) in the NF-κB pathway of leukemia and lymphoma. The ubiquitin-proteasome system (UPS) is a critical c...

    Authors: Mahdi Pakjoo, Seyed Esmaeil Ahmadi, Mohammad Zahedi, Niloofar Jaafari, Reyhane Khademi, Ali Amini and Majid Safa
    Citation: Cell Communication and Signaling 2024 22:105
  41. Extravasation is a fundamental step in the metastatic journey, where cancer cells exit the bloodstream and breach the endothelial cell barrier to infiltrate target tissues. The tactics cancer cells employ are ...

    Authors: Sara Di Russo, Francesca Romana Liberati, Agnese Riva, Federica Di Fonzo, Alberto Macone, Giorgio Giardina, Marzia Arese, Serena Rinaldo, Francesca Cutruzzolà and Alessio Paone
    Citation: Cell Communication and Signaling 2024 22:104
  42. Neutrophil extracellular traps (NETs) have garnered attention for their dual role in host defense and tumor promotion. With their involvement documented across a spectrum of tumors, their influence on the prog...

    Authors: Congyi Zhang, Dehai Wu, Bowen Dong, Guanqun Liao, Yang Yu, Shizhuan Huang, Feng Luo, Bin Zhang, Haotian Wu, Tianwei Li, Dixiang Wen and Sheng Tai
    Citation: Cell Communication and Signaling 2024 22:103
  43. Protein arginine methyltransferase 1 (PRMT1), the predominant type I protein arginine methyltransferase, plays a crucial role in normal biological functions by catalyzing the methylation of arginine side chain...

    Authors: Shiquan Shen, Honglong Zhou, Zongyu Xiao, Shaofen Zhan, Yonghua Tuo, Danmin Chen, Xiao Pang, Yezhong Wang and Ji Wang
    Citation: Cell Communication and Signaling 2024 22:102
  44. Our previous studies demonstrated that 1-Pyrroline-5-carboxylate (P5C) released by prostate cancer cells inhibits T cell proliferation and function by increasing SHP1 expression. We designed this study to furt...

    Authors: Lei Chang, Guohao Li, Shan Jiang, Jie Li, Jin Yang, Kavita Shah, Le Zhou, Hanrui Song, Leyuan Deng, Zhiguo Luo, Yonglian Guo and Yutao Yan
    Citation: Cell Communication and Signaling 2024 22:101
  45. Invasive ductal carcinoma (IDC) is the most common form of breast cancer which accounts for 85% of all breast cancer diagnoses. Non-invasive and early stages have a better prognosis than late-stage invasive ca...

    Authors: Vinod Kumar Verma, Syed Sultan Beevi, Rekha A. Nair, Aviral Kumar, Ravi Kiran, Liza Esther Alexander and Lekha Dinesh Kumar
    Citation: Cell Communication and Signaling 2024 22:100
  46. The changes in T regulatory cell (Treg) and T helper cell (Th) 17 ratios holds paramount importance in ensuring internal homeostasis and disease progression. Recently, novel subsets of Treg and Th17, namely IL...

    Authors: Huantian Cui, Ning Wang, Hanzhou Li, Yuhong Bian, Weibo Wen, Xiangying Kong and Fudi Wang
    Citation: Cell Communication and Signaling 2024 22:99

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