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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

Fig. 2

 N-glycans of FGFs are recognized by galectins. A-D BLI analyses of the interaction between N-glycosylated and de-glycosylated FGFs and galectins. N-glycosylated and enzymatically de-glycosylated FGFs: FGF4-Fc (A), FGF9-Fc (B), FGF10-Fc (C) and FGF18-Fc (D) were immobilized on Protein-A biosensors (blue lines) in a pairwise fashion with equimolar concentrations of PNGase F-treated FGF4-Fc, FGF9-Fc, FGF10-Fc and FGF18-Fc, respectively (red lines), and the association and dissociation phases were recorded with BLI. Representative results from at least three independent experiments are shown

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Cell Communication and Signaling

ISSN: 1478-811X