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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Autophagy modulators influence the content of important signalling molecules in PS-positive extracellular vesicles

Fig. 6

Protein content of PS-EVs. (a) Representation of proteins contained in PS-EVs in biological processes and cellular components. The most abundant proteins in PS-EVs were proteins typical for extracellular exosomes, cytosol, cytoplasm, and cell surface involved in cell adhesion, angiogenesis, and apoptotic processes. PG = protein group (b) Categories from the GO database. Changes in biological processes and the representation of PS-EVs proteins in particular cellular compartments caused by autophagy modulators. (c) Autophagy modulators change the levels of p62/SQSTM1 in PS-EVs. Bafilomycin and HCQ treatment induces the inclusion of p62/SQSTM1 into PS-EVs. PG = protein group (d) Autophagy modulators significantly change the representation of mitochondrial proteins in PS-EVs. PG = protein group (e) Autophagy modulators significantly change the representation of some Rab proteins in PS-EVs

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Cell Communication and Signaling

ISSN: 1478-811X