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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity

Fig. 1

EIF5A2 overexpression in LUAD is associated with poor survival. A Genomic alterations of EIF5A1 and EIF5A2 analysis using the dataset of TCGA Pan-Cancer Atlas Studies at the cBioPortal for Cancer Genomics. Green, mutation; red, amplification; blue, deep deletion. B Survival prognostic curve in patients with LUAD is shown. C eIF-5A2 localises in the nucleus, perinucleus and cytoplasm of cancer cells. In normal lung tissues eIF-5A2 is expressed in alveolar walls and cytoplasm of alveolar macrophages. Tissue microarray immunohistochemistry of the samples from patients LF01, LF05, LF09, LF15, LF19, LF20, LF21 and LF29 [35]. Normal lung tissue adyacent to primary tumor and primary tumor tissue are shown. Images show Hematoxylin and eosin (H&E) staining along immunohistochemistry with the anti-eIF-5A2 antibody. Sale bar for 5X images are 500 µm; scale bar for 20X images are 100 µm

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Cell Communication and Signaling

ISSN: 1478-811X