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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration

Fig. 2

The overexpression of MMP19 aggravates BLM-induced mouse lung fibrosis. A Weight changes of MMP19WT- and MMP19E213A-AAV-infected mice treated with saline control or BLM. n = 4 in all groups. B Dry lung weight of MMP19WT- and MMP19E213A-AAV-infected mice treated with saline control or BLM. n = 4 in all groups. C Lung hydroxyproline levels in MMP19WT- and MMP19E213A-AAV-infected mice treated with saline control or BLM. n = 3 in all groups. D Representative micrographs of H&E staining, Masson’s trichrome and immunohistochemical staining of lung sections for ɑ-SMA

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