Skip to main content
Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Cell adhesion molecule BVES functions as a suppressor of tumor cells extrusion in hepatocellular carcinoma metastasis

Fig. 4

BVES downregulation enhanced HCC cells extrusion. A Western blot analysis of the expression of BVES after plasmids transfection. B The number of extrusion cells of Huh7 cells with BVES knockdown and SK-Hep-1 cells/SMMC-7721 with BVES overexpression in the silicone chamber model. C Representative images of cell clones in the large culture dish of extruded indicated cells in the petri dish inversion model. D The clone numbers of extruded indicated cells in the large culture dish of extruded indicated cells in the petri dish inversion model. E GFP-labeled HCC cells were mixed with HL7702 cells at a ratio of 1:100 to grow to confluence in the petri dish inversion model. The number of cells remained in the small dish inversely correlated with the number of extruded HCC cells (× 40). Representative images of the remaining indicated HCC cells in the small dish per field of vision. F The number of remaining indicated HCC cells in the small dish per field of vision. Bars represent mean ± S.D. of three independent experiments, *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X