Fig. 4
From: STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis
Jak2/STAT3 signal network regulates osteoclastic differentiation. JAK/STAT3 signaling pathway mediated network in regulating osteoclastic differentiation of BMMs with either some members of interleukins or other agents, marked with event-specific colored line or arrows. Those delineated in a rectangle with dotted line indicate functional similarity. Ending with red bars indicate inhibition or downregulation, arrows indicate positive stimulation or upregulation