| |
Higher expression of NEK2 (n = 57)
|
Lower expression of NEK2 (n = 46)
|
P
|
|---|
|
Sex, Male (%)
|
49 (86.0)
|
36 (78.3)
|
0.446
|
|
Age (mean (SD))
|
66.61 (9.47)
|
64.61 (7.40)
|
0.243
|
|
Size (mean (SD))
|
4.70 (1.79)
|
4.83 (1.77)
|
0.717
|
|
Location (%)
| | |
0.779
|
|
Middle
|
46 (80.7)
|
39 (84.8)
| |
|
Others
|
10 (19.3)
|
8 (15.2)
| |
|
Morphology (%)
| | |
0.111
|
|
Plaque
|
11 (19.3)
|
5 (10.9)
| |
|
Fungoid
|
12 (21.1)
|
14 (30.4)
| |
|
Ulcerative
|
0 (0.0)
|
3 (6.5)
| |
|
Medullary
|
34 (59.6)
|
24 (52.2)
| |
|
Grade (%)
| | |
0.001
|
|
G1
|
2 (3.5)
|
13 (28.3)
| |
|
G2
|
40 (70.2)
|
28 (60.9)
| |
|
G3
|
15 (26.3)
|
5 (10.8)
| |
|
Invasion depth (%)
| | |
0.557
|
|
Submucosal
|
1 (1.8)
|
2 (4.3)
| |
|
Muscular
|
14 (24.6)
|
14 (30.4)
| |
|
Serosa
|
42 (73.7)
|
30 (65.2)
| |
|
Lymph node metastasis
| | |
0.029
|
|
Yes
|
34 (59.6)
|
17 (37.0)
| |
|
No
|
23 (40.4)
|
29 (63.0)
| |
|
T stage (%)
| | |
0.462
|
|
T1
|
1 (1.8)
|
2 (4.3)
| |
|
T2
|
13 (22.8)
|
13 (28.3)
| |
|
T3
|
41 (71.9)
|
31 (67.4)
| |
|
T4
|
2 (3.5)
|
0 (0.0)
| |
|
N stage (%)
| | |
0.065
|
|
N0
|
23 (40.4)
|
29 (63.0)
| |
|
N1
|
20 (35.1)
|
11 (23.9)
| |
|
N2
|
10 (17.5)
|
6 (13.0)
| |
|
N3
|
4 (7.0)
|
0 (0.0)
| |
|
Metastasis
|
0
|
0
| |
|
AJCC* stage (%)
| | |
0.001
|
|
I
|
1 (1.8)
|
5 (10.9)
| |
|
II
|
22 (38.6)
|
24 (52.2)
| |
|
III
|
27 (47.4)
|
17 (37.0)
| |
|
IV
|
7 (12.3)
|
0 (0.0)
| |
- *AJCC The 8th Version of American Joint Committee on Cancer
