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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy

Fig. 6

MAP4 phosphorylation induced EMT in podocyte. A Identification of adenovirus efficacy of MAP4(Ala) or MAP4(Glu). B, C Representative WB (B) and quantitative analysis (C) showing the epithelial and mesenchymal cell markers of podocyte after MAP4(Ala) or MAP4(Glu) transfection with or without HG stimulation. D, E Representative confocal immunofluorescence images (D) and quantitative analysis (E) showing the epithelial and mesenchymal cell markers of podocyte after MAP4(Ala) or MAP4(Glu) transfection with or without HG stimulation. Bar, 25 µm. MPC5, cell line of mouse podocyte. Data were shown as mean ± SEM. The experiment was conducted 6 times. *P < 0.05, **P < 0.01, ***P < 0.001. P values were derived from one-way ANOVA with Bonferroni’s post-test

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