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Table 2 Clinical characteristics of participants by study group

From: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome

Parameters

PCOS group n = 6

Control group n = 6

Difference between groupsa

Mean (± SD)

Mean (± SD)

Adjusted mean difference (95%CI)b

p value

q value

Age

30.250 (4.3725)

27.429 (2.507)

0.71 (− 0.26 to 1.67)

0.139

0.175

Years of infertility

3.750 (1.960)

2.429 (0.976)

0.75 (− 0.22 to 1.72)

0.116

0.168

Body mass index (BMI)c

23.390 (2.131)

22.366 (2.202)

0.45 (− 0.49 to 1.40)

0.332

0.319

Luteinizing hormone (LH) IU/Ld

13.077 (3.741)

5.029 (1.924)

2.39 (1.12 to 3.65)

 < 0.001

 < 0.001

Follicle stimulating hormone (FSH) IU/Ld

5.178 (1.303)

6.410 (1.903)

 − 0.76 (− 1.73 to 0.21)

0.111

0.168

LH:FSH ratio

2.514 (0.399)

0.804 (0.278)

4.52 (2.66 to 6.39)

 

 < 0.001

Estradiol (E2) pmol/Ld

147.4 (38.756)

140.057 (146.376)

0.08 (− 0.86 to 1.01)

0.870

0.678

Testosterone nmol/L

2.023 (0.287)

0.697 (0.334)

4.16 (2.41 to 5.92)

 < 0.001

 < 0.001

Prolactin (PRL)mIU/Ld

349.016 (214.871)

363.9 (132.897)

 − 0.08 (− 1.02 to 0.87)

0.873

0.678

Anti-mullerian hormone (AMH)ng/ml

9.933 (5.628)

4.450 (1.800)

1.13 (0.11 to 2.14)

0.024

0.048

Progesterone (P)nmol/L

0.452 (0.275)

0.657 (0.653)

 − 0.44 (− 1.38 to 0.51)

0.347

0.319

Fasting glucose nmol/L

5.023 (0.412)

5.216 (0.296)

 − 0.49 (− 1.44 to 0.46)

0.294

0.319

Sinus follicle number

32.167 (10.098)

20.857 (4.981)

1.25 (0.22 to 2.28)

0.014

0.034

  1. aAll results are reported after adjustment for baseline values using ANCOVA
  2. bIntervention effects are quantified as differences between groups in the mean value for each scale, estimated using linear regression models that adjusted for recruitment site and language of interview
  3. cBMI = bodyweight (kg) divided by height (metres) squared. (BMI = w(kg)/height(m)2)
  4. dLog transformations were carried out on the data before analyses