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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome

Fig. 7

The expression changes of miR-155-5p can affect the glycolysis and proliferation of KGN cells. A qPCR analysis of miR-155-5p expression in cell models. B qPCR analysis of the expression of key DEGs (HK2, PKM2, LDHA) in cell models in a control environment. C qPCR analysis of the expression of key DEGs (HK2, PKM2, LDHA) in cell models in a PCOS environment. D Western blot analysis of HK2 in cell models. E Western blot analysis of PKM2 in cell models. F Western blot analysis of LDHA in cell models. G Metabolic concentration of pyruvate in cell model medium. H Metabolic concentration of lactate in cell model medium. I Culture medium characterization of the cell model. J qPCR analysis of Bcl2/Bax in cell models. K Western blot analysis of Bcl2/Bax in cell models. L EdU shows the proliferation index of the cell model (ns = not significant, *p < 0.05, **p < 0.01 and ***p < 0.001)

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Cell Communication and Signaling

ISSN: 1478-811X