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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome

Fig. 5

The state of KGN cells with PCOS environment changes. A The expression of miR-143-3p and miR-155-5p in exosomes was analysed by RNA-seq. B The expression of exosomal miR-143-3p and miR-155-5p was analysed by qPCR. C The expression of miR-143-3p and miR-155-5p in KGN cells was analysed by qPCR. D The expression of glycolytic DEGs (HK2, PKM2 and LDHA) in KGN cells was analysed by qPCR. E Concentration of glycolytic products in KGN cell culture medium. F Culture medium characterization of KGN cells. G The Bcl2/Bax expression ratio was analysed by qPCR. H EDU shows the cell proliferation index (*p < 0.05, **p < 0.01, ***p < 0.001)

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