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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: CCL7 playing a dominant role in recruiting early OCPs to facilitate osteolysis at metastatic site of colorectal cancer

Fig. 6

Treatment of CCR1 siRNA attenuated osteolysis in bone metastasis of MC-38. A, B Safranin O and fast green staining showed the trabecular area at 14 days post injection of MC-38 after treatment with CCR1 siRNA or scRNA (Scale bar = 50 μm) (A) and quantification of trabecular area (B). n = 6. C, D TRAP staining showed OC surface at 14 days post injection of MC-38 after treatment with CCR1 siRNA or scRNA (Scale bar = 50 μm) (C) and quantification of OC surface/trabecular area (D). n = 6. E Prognosis of mice after treatment with siCCR1 after injection of MC-38 cells. ***p < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X