Fig. 2
From: Intrinsically disordered proteins play diverse roles in cell signaling
Intrinsic disorder predisposition of human glucocorticoid receptor (UniProt ID: P04150) evaluated by PONDR® VSL2 [179], PONDR® VL3 [180], PONDR® VLXT [6], PONDR® FIT [181], IUPred2A_long and IUPred2A_short [181, 182]. Mean disorder score is shown as well. Positions of the N-terminal domain (residues 1–420), DNA binding domain (residues 420–485), a hinge region (residues 486–527), and ligand binding domain (residues 528–777) are shown as red, cyan, blue and lime shaded areas. Clearly, the N-terminal domain and a hinge region are mostly disordered