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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Endoplasmic reticulum stress promotes the release of exosomal PD-L1 from head and neck cancer cells and facilitates M2 macrophage polarization

Fig. 1

ER stress is activated in the OSCC tissues. A Representative immunohistochemical images of the ER stress marker (PERK, ATF6, and GRP78) staining in the paraneoplastic tissues (NT) and OSCC tissues (TT) of patients with OSCC (scale bar = 50 μm) (n = 3). B–D Quantification of PERK (B), ATF6 (C), and GRP78-positive (D) staining in (A) (n = 3). E Western blot analyses of PERK, ATF6, and GRP78 protein expression in the paraneoplastic tissues (NT) and OSCC tissues (TT) of patients with OSCC. F–H Quantification of the protein levels of PERK (F), ATF6 (G), and GRP78 (H) in (E). I–K The level of PERK (I), ATF6 (J), and GRP78 mRNA (K) in the paraneoplastic tissues (NT) and OSCC tissues (TT) of patients with OSCC (n = 3) (**P < 0.01 and ***P < 0.001)

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