Skip to main content
Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Interleukin-1 receptor antagonist inhibits metastatic potential by down-regulating CXCL12/CXCR4 signaling axis in colorectal cancer

Fig. 1

Expression levels of CXCL12, CXCR4, IL-1α and IL-1 RI in colorectal cancer cell lines and stromal cells, and siRNA blockage of CXCR4 expression in colorectal cancer cell lines. Expression levels of CXCL12, CXCR4 and IL-1α mRNA and protein in four human colorectal cancer cell lines and fibroblasts were detected by reverse transcription (RT)-PCR (A) and Western blotting (B), respectively. The CXCR4 protein expression level in four colorectal cancer cells transfected with CXCR4 gene-targeted small interfering RNA (CXCR4 siRNA) was detected by western blotting (C). β-actin was used as an control

Back to article page