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Table3 HCC1954 combination index data for HGF + EGF

From: Functional signaling test identifies HER2 negative breast cancer patients who may benefit from c-Met and pan-HER combination therapy

HGF (pM)

EGF (pM)

Fraction activated (%)

Combination Index

50

300

92.8

1.43

10

60

58.9

1.81

2

12

25.7

1.25

0.4

2.4

8.7

0.8

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Cell Communication and Signaling

ISSN: 1478-811X