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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: The protective effects of pericyte-derived microvesicles on vascular endothelial functions via CTGF delivery in sepsis

Fig. 3

Protective effect of PMVs on LPS-stimulated VECs. A Laser confocal microscopy analysis of the absorption of PKH-26 labeled PMVs and SMVs in VECs, the representative microimages are shown (n = 3, bar = 10 μm). B Scratch experiment of VECs, effect of PMVs on migration ability is shown (n = 5, bar = 100 μm). C CCK8 proliferation of VECs (n = 6). D The expression of PCNA in VECs (n = 3). E Tube formation of VECs, the representative images are shown (n = 5, bar = 50 μm). F Statistical data of the tube length in (E) (n = 5). G Transendothelial electrical resistance (TER) of VECs (n = 3). H FITC-BSA leakage in VECs (n = 3). I Laser confocal microscopy analysis of ZO-1 in VECs, the representative images are shown (n = 5, bar = 20 μm). J Laser confocal microscopy analysis of Tunel assay in VECs, the representative images are shown (n = 5, bar = 50 μm). Ctl: normal group; LPS: LPS group; SMV: SMV-treated LPS group; PMV: PMV-treated LPS group. ***P < 0.001; **P < 0.01

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