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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Multiomic analysis on human cell model of wolfram syndrome reveals changes in mitochondrial morphology and function

Fig. 2

Pathways significantly expressed in WFS patients compared to control. A Enrichment map presenting Reactome Gene Sets significant in comparison: WFS versus healthy. Upregulated pathways are shown in red and downregulated ones in blue. B Enrichment plot and heatmap of Reactome mitochondrial protein import Gene Set. Heatmap depicts the genes that comprise the pathway with red tiles representing increased expression in WFS versus controls. C Enrichment plot and heatmap of Reactome respiratory electron transport Gene Set. D Graphical summary of pathways significantly expressed in WFS

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