Fig. 6
From: EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression
KISS1 and ID3 expression levels are upregulated in the placenta of PE patients. a, b, Serum samples were collected from 17 PE patients and 16 normal pregnant women of similar age and gestational age. The age and gestational age of the included patients are presented (a). body mass index (BMI), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured (b). c Serum levels of EGF were measured by ELISA. d Serum levels of KISS1 were measured by ELISA. e, f Representative images of immunohistochemical staining for KISS1 (e) and ID3 (f) in the control and PE placenta. Original magnification: ×200. The scale bar represents 50 μm. The clinical results are expressed as the mean ± SD