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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Zinc-mediated activation of CREB pathway in proliferation of pulmonary artery smooth muscle cells in pulmonary hypertension

Fig. 2

The effect of MCT on the expression and phosphorylation of CREB. a The elevated CREB phosphorylation in lung tissues. The lung tissues were isolated from control and rats treated with MCT for 1, 2, 3 and 4 weeks. n = 7. b The CREB phosphorylation and expression in PASMCs derived from control and rats treated with MCT for 1, 2, 3 and 4 weeks. n = 7. c Immunofluorescence staining showed the increased phosphorylation of CREB (red staining) in the distal pulmonary arteries. n = 5. d The increased entry of phosphorylated-CREB (green staining) in PH-PASMCs, revealed by immunofluorescence staining. n = 3. *p < 0.05 versu Ctr

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Cell Communication and Signaling

ISSN: 1478-811X