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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired progenitor stem cells

Fig. 5

Evaluation of mitochondria condition and antioxidative defence during adipogenesis. Mitochondrial membrane potential was evaluated with MUSE cell analyser (a) allowing for the determination of the number of cells with depolarised mitochondria (b). Antioxidative properties of the cells were tested by the determination of CAT, SOD1, and SOD2 expression (c). Additionally, the obtained results were shown in part of a whole graph (d). Results are expressed as mean ± SD; n = 3. Statistical significance indicated as asterisk (*) when comparing the result to ASCs HE and as number sign (#) when compared to ASCs EMS. p < 0.001

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