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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression

Fig. 1

MB49 cells conditioned medium could promote the transformation of BMDM to M2 phenotype. A The expression of Il-10, Cd206, Tgfb and Inos was quantified by qRT-PCR in macrophages stimulated with MB49 cells conditioned medium for 12 and 24 h, respectively. Results are present as the means ± SD of 3 independent experiments. Data were analyzed by one-way ANOVA with multiple comparisons test (*P < 0.05, **P < 0.01, ****P < 0.0001). B BMDM were stimulated with MB49 conditioned medium for 48 h, and the proportion of F4/80+CD206+ cells was detected by flow cytometry. Representative images of each sample are shown. Data were analyzed by t-test (Mean ± SD, n = 3, ***P < 0.001)

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