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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway

Fig. 7

Inhibiting PI3K-Akt pathway in glioblastoma-derived EVs-treated mNPCs reversed elevated NPC proliferation. Wortamnnin significantly reversed U87-EVs-elevated proportion of EdU-positive cells in U87-EVs-treated mNPCs. Wortamnnin significantly reversed U87-EVs-elevated proportion of Ki67-positive cells in U87 EVs-treated mNPCs. Results are presented as the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01, and ****p < 0.0001. Scale bar, 100 μm

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