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Table 1 α- and β-adrenoceptor distribution and expression in different human tissues

From: Role of α- and β-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease

Subtypes of receptors functional in adrenergic signaling in target tissues

Adrenoceptor subtype

Tissue RNA expression and distribution in different organs

α-adrenoceptors

α-1A adrenoceptor

1. Liver

2. Adipose tissue

3. Prostate

4. Seminal vesicles

5. Spleen

α-1B adrenoceptor

1. Spleen

2. Cerebral cortex

3. Liver

4. Ovary

5. Kidney

α-1D adrenoceptor

1. Prostate

2. Cervix, uterine

3. Seminal vesicles

4. Spleen

5. Fallopian tube

β-adrenoceptors

β-B1 adrenoceptors

1. Placenta

2. Heart

3. Lung

4. Prostate

5. Cerebral cortex

β-B2 adrenoceptors

1. T-cells

2. Granulocytes

3. Monocytes

4. NK-cells

5. Lung

β-B3 adrenoceptors

1. Ovary

2. Placenta

3. Gallbladder

4. Urinary bladder

5. Epididymis

  1. Comparative cell type localization and presence of different subtypes of α-and β-adrenoceptors in different tissue types of human body. Top 5 ranked tissue by RNA expression are shown
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Cell Communication and Signaling

ISSN: 1478-811X