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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Single-cell analysis reveals cell communication triggered by macrophages associated with the reduction and exhaustion of CD8+ T cells in COVID-19

Fig. 4

BAI macrophage subpopulations. a t-SNE plot showing macrophage subpopulations. b Percentage of the subpopulation of macrophages derived from patients with COVID-19 across different conditions. c Expression of marker genes across macrophage subtypes as visualized on t-SNE (upper) and violin plots. d The difference of cytokine expression levels between moderate and severe groups. e Hypoxia scores of macrophages derived from moderate and severe samples. f Hypoxia score enriched in each of macrophage subpopulation, the score of subpopulations were respectively compared to M0. * p < 0.05, ** p < 0.01, *** p < 0.001 (Student’s t test)

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