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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Single-cell analysis reveals cell communication triggered by macrophages associated with the reduction and exhaustion of CD8+ T cells in COVID-19

Fig. 2

The phenotypes and counts of T cell subtypes. a, b Fluorescence-activated cell sorting (FACS) dot plot examples, gated on total CD45+ cells (left), the expression of CD4 and/ or CD3 on CD45+ cells (middle), and the expression of CD8 and/ or CD3 on CD45+ cells (right). Case A indicates one of the moderate patients with COVID-19 (a). Case B, one representative case of severe patients (b). c, d The violin graph showing the counts of CD4+ T cells (c) and CD8+ T cells (d) in patients with different groups. *** p < 0.001 (Student’s t-test). e ROCs are created by plotting the true positive rate (TPR) against the false positive rate (FPR) at various threshold settings with corresponding AUCs labeled around the curves

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