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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Effect of HSP90AB1 and CC domain interaction on Bcr-Abl protein cytoplasm localization and function in chronic myeloid leukemia cells

Fig. 1

Identification of HSP90AB1 as a Bcr/Abl binding partner. a Total cell extracts prepared from 293 T cells expressing HA-tagged Bcr/Abl, HA-tagged Bcr/Abl-ΔCC or vector alone were subjected to immunoprecipitation using anti-HA beads. Proteins were resolved by SDS-PAGE and visualized by silver staining. b The proteins selected by LC/MS–MS were classified according to their related functions, and the differential proteins related to protein subcellular localization were screened out through GO_CC. c LC/MS–MS spectrometry of the purified HA-Bcr/Abl–associated peptides corresponding to HSP90AB1

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Cell Communication and Signaling

ISSN: 1478-811X