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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition

Fig. 5

Cell signals that regulate SFKs input into major cellular pathways. Roles of SFKs in modulating some of the key EMT-inducing pathways. Top, Signals initiated by a variety of receptors, TGF-beta, WNT pathway receptors (LRP5/6), Notch and growth factor receptors such as EGFR. All signals involve cytoplasmic regulators and modulators which end up activating transcription factors/coactivators to regulate gene expression. See text for details. Created with BioRender.com

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