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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Patient-derived scaffolds influence secretion profiles in cancer cells mirroring clinical features and breast cancer subtypes

Fig. 5

Subgroups of PDSs created by unsupervised clustering based on secretion from MCF7 cells. a PDSs cultivated with MCF7 cells (n = 57) divided into three groups, SOM1 (blue), SOM2 (green) and SOM3 (orange), based on cancer cell secretion by an unsupervised clustering method of a self-organizing map (SOM). b Principal component analysis (PCA) scores illustrating the PDSs (n = 57) cultivated with MCF7 cells divided into three groups, SOM1 (blue), SOM2 (green) and SOM3 (orange). c–e Boxplot illustrating key proteins for subgroup formation of c SOM1, d SOM2 and e SOM3, the data is autoscaled and error bars show the minimum and the maximum values

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Cell Communication and Signaling

ISSN: 1478-811X