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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Bone morphogenetic protein receptor 2 inhibition destabilizes microtubules promoting the activation of lysosomes and cell death of lung cancer cells

Fig. 5

Inhibition of BMPR2 destabilizes the microtubules. A, B Immunofluorescence imaging for α-tubulin of A549 and H1299 cells treated with JL5 or Ym155. C, D Immunofluorescence imaging for acetylated α-tubulin of A549 and H1299 cells treated with JL5 or Ym155. E Immunofluorescence imaging for α-tubulin in MDA-MB-468 cells treated with JL5 or Ym155. F, G Immunofluorescence imaging for α-tubulin in A549 and H1299 cells treated with the BMPR1 inhibitor DMH1. H Immunofluorescence imaging for α-tubulin following knockdown of BMPR2 after 48 h. Each scale bar represents 10 μM

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Cell Communication and Signaling

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