Skip to main content
Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Multi-omics analysis of tumor angiogenesis characteristics and potential epigenetic regulation mechanisms in renal clear cell carcinoma

Fig. 7

Master transcription factors in regulating angiogenesis signal of TCGA KIRC patients. a Motif enrichment analysis showed that NFIA and NFIC shared the highest odds ratio value and percentage; b, c transcription factors including RFX2, SOX13, and THRA were identified as TOP3 master TFs in both NFIA and NFIC motif; Higher RFX2 (d), SOX13 (e), and THRA (f) expression in KIRC patients were associated with better OS according to Kaplan–Meier survival log-rank test; g compared with Cluter_2, RCC patients in Cluster_1 showed higher RFX2, SOX13, and THRA expression. * represent P value less than 0.05

Back to article page