TY - JOUR AU - Al Zaabi, N. AU - Al Menhali, N. AU - Al-Jasmi, F. PY - 2018 DA - 2018// TI - SYNJ1 gene associated with neonatal onset of neurodegenerative disorder and intractable seizure JO - Mol Genet Genom Med VL - 6 UR - https://doi.org/10.1002/mgg3.341 DO - 10.1002/mgg3.341 ID - Al Zaabi2018 ER - TY - JOUR AU - Antonietta Ajmone-Cat, M. AU - Lavinia Salvatori, M. AU - Simone, R. AU - Mancini, M. AU - Biagioni, S. AU - Bernardo, A. AU - Cacci, E. AU - Minghetti, L. PY - 2012 DA - 2012// TI - Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells JO - J Neurosci Res VL - 90 UR - https://doi.org/10.1002/jnr.22783 DO - 10.1002/jnr.22783 ID - Antonietta Ajmone-Cat2012 ER - TY - JOUR AU - Araki, N. AU - Egami, Y. AU - Watanabe, Y. AU - Hatae, T. PY - 2007 DA - 2007// TI - Phosphoinositide metabolism during membrane ruffling and macropinosome formation in EGF-stimulated A431 cells JO - Exp Cell Res VL - 313 UR - https://doi.org/10.1016/j.yexcr.2007.02.012 DO - 10.1016/j.yexcr.2007.02.012 ID - Araki2007 ER - TY - JOUR AU - Arancio, O. PY - 2008 DA - 2008// TI - PIP2: a new key player in Alzheimer’s disease JO - Cellscience VL - 5 ID - Arancio2008 ER - TY - JOUR AU - Arnés, M. AU - Romero, N. AU - Casas-Tintó, S. AU - Acebes, Á. AU - Ferrús, A. PY - 2020 DA - 2020// TI - PI3K activation prevents Aβ42-induced synapse loss and favors insoluble amyloid deposit formation JO - Mol Biol Cell VL - 31 UR - https://doi.org/10.1091/mbc.E19-05-0303 DO - 10.1091/mbc.E19-05-0303 ID - Arnés2020 ER - TY - JOUR AU - Bazinet, R. P. AU - Layé, S. PY - 2014 DA - 2014// TI - Polyunsaturated fatty acids and their metabolites in brain function and disease JO - Nat Rev Neurosci VL - 15 UR - https://doi.org/10.1038/nrn3820 DO - 10.1038/nrn3820 ID - Bazinet2014 ER - TY - JOUR AU - Berman, D. E. AU - Dall'Armi, C. AU - Voronov, S. V. AU - McIntire, L. B. J. AU - Zhang, H. AU - Moore, A. Z. AU - Staniszewski, A. AU - Arancio, O. AU - Kim, T. -. W. AU - Paolo, G. PY - 2008 DA - 2008// TI - Oligomeric amyloid-β peptide disrupts phosphatidylinositol-4, 5-bisphosphate metabolism JO - Nat Neurosci VL - 11 UR - https://doi.org/10.1038/nn.2100 DO - 10.1038/nn.2100 ID - Berman2008 ER - TY - JOUR AU - Botelho, R. J. AU - Teruel, M. AU - Dierckman, R. AU - Anderson, R. AU - Wells, A. AU - York, J. D. AU - Meyer, T. AU - Grinstein, S. PY - 2000 DA - 2000// TI - Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis JO - J Cell Biol VL - 151 UR - https://doi.org/10.1083/jcb.151.7.1353 DO - 10.1083/jcb.151.7.1353 ID - Botelho2000 ER - TY - JOUR AU - Botelho, R. J. AU - Teruel, M. AU - Dierckman, R. AU - Anderson, R. AU - Wells, A. AU - York, J. D. AU - Meyer, T. AU - Grinstein, S. PY - 2000 DA - 2000// TI - Localized biphasic changes in phosphatidylinositol-4, 5-bisphosphate at sites of phagocytosis JO - J Cell Biol VL - 151 UR - https://doi.org/10.1083/jcb.151.7.1353 DO - 10.1083/jcb.151.7.1353 ID - Botelho2000 ER - TY - JOUR AU - Braun, V. AU - Fraisier, V. AU - Raposo, G. AU - Hurbain, I. AU - Sibarita, J. B. AU - Chavrier, P. AU - Galli, T. AU - Niedergang, F. PY - 2004 DA - 2004// TI - TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages JO - EMBO J VL - 23 UR - https://doi.org/10.1038/sj.emboj.7600427 DO - 10.1038/sj.emboj.7600427 ID - Braun2004 ER - TY - JOUR AU - Brown, F. D. AU - Rozelle, A. L. AU - Yin, H. L. AU - Balla, T. AU - Donaldson, J. G. PY - 2001 DA - 2001// TI - Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic JO - J Cell Biol VL - 154 UR - https://doi.org/10.1083/jcb.200103107 DO - 10.1083/jcb.200103107 ID - Brown2001 ER - TY - JOUR AU - Campeau, P. M. AU - Lenk, G. M. AU - Lu, J. T. AU - Bae, Y. AU - Burrage, L. AU - Turnpenny, P. AU - Román Corona-Rivera, J. AU - Morandi, L. AU - Mora, M. AU - Reutter, H. PY - 2013 DA - 2013// TI - Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase JO - Am J Hum Genet VL - 92 UR - https://doi.org/10.1016/j.ajhg.2013.03.020 DO - 10.1016/j.ajhg.2013.03.020 ID - Campeau2013 ER - TY - JOUR AU - Canevari, L. AU - Abramov, A. Y. AU - Duchen, M. R. PY - 2004 DA - 2004// TI - Toxicity of amyloid β peptide: tales of calcium, mitochondria, and oxidative stress JO - Neurochem Res VL - 29 UR - https://doi.org/10.1023/B:NERE.0000014834.06405.af DO - 10.1023/B:NERE.0000014834.06405.af ID - Canevari2004 ER - TY - CHAP AU - Castellano, E. AU - Downward, J. ED - Rommel, C. ED - Vanhaesebroeck, B. ED - Vogt, P. K. PY - 2010 DA - 2010// TI - Role of RAS in the regulation of PI 3-kinase BT - Phosphoinositide 3-kinase in health and disease PB - Springer CY - New York UR - https://doi.org/10.1007/82_2010_56 DO - 10.1007/82_2010_56 ID - Castellano2010 ER - TY - JOUR AU - Chen, G. -. F. AU - Xu, T. -. H. AU - Yan, Y. AU - Zhou, Y. -. R. AU - Jiang, Y. AU - Melcher, K. AU - Xu, H. E. PY - 2017 DA - 2017// TI - Amyloid beta: structure, biology and structure-based therapeutic development JO - Acta Pharmacol Sin VL - 38 UR - https://doi.org/10.1038/aps.2017.28 DO - 10.1038/aps.2017.28 ID - Chen2017 ER - TY - JOUR AU - Chen, S. AU - Zhang, H. AU - Pu, H. AU - Wang, G. AU - Li, W. AU - Leak, R. K. AU - Chen, J. AU - Liou, A. K. AU - Hu, X. PY - 2014 DA - 2014// TI - n-3 PUFA supplementation benefits microglial responses to myelin pathology JO - Sci Rep VL - 4 UR - https://doi.org/10.1038/srep07458 DO - 10.1038/srep07458 ID - Chen2014 ER - TY - JOUR AU - Chen, T. J. AU - Wang, D. C. AU - Chen, S. S. PY - 2009 DA - 2009// TI - Amyloid-β interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons JO - J Neurosci Res VL - 87 UR - https://doi.org/10.1002/jnr.22057 DO - 10.1002/jnr.22057 ID - Chen2009 ER - TY - JOUR AU - Chow, C. Y. AU - Zhang, Y. AU - Dowling, J. J. AU - Jin, N. AU - Adamska, M. AU - Shiga, K. AU - Szigeti, K. AU - Shy, M. E. AU - Li, J. AU - Zhang, X. PY - 2007 DA - 2007// TI - Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J JO - Nature VL - 448 UR - https://doi.org/10.1038/nature05876 DO - 10.1038/nature05876 ID - Chow2007 ER - TY - JOUR AU - Coppolino, M. G. AU - Dierckman, R. AU - Loijens, J. AU - Collins, R. F. AU - Pouladi, M. AU - Jongstra-Bilen, J. AU - Schreiber, A. D. AU - Trimble, W. S. AU - Anderson, R. AU - Grinstein, S. PY - 2002 DA - 2002// TI - Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M209046200 DO - 10.1074/jbc.M209046200 ID - Coppolino2002 ER - TY - JOUR AU - Corsi, L. AU - Dongmo, B. M. AU - Avallone, R. PY - 2015 DA - 2015// TI - Supplementation of omega 3 fatty acids improves oxidative stress in activated BV2 microglial cell line JO - Int J Food Sci Nutr VL - 66 UR - https://doi.org/10.3109/09637486.2014.986073 DO - 10.3109/09637486.2014.986073 ID - Corsi2015 ER - TY - JOUR AU - Cossec, J. C. AU - Lavaur, J. AU - Berman, D. E. AU - Rivals, I. AU - Hoischen, A. AU - Stora, S. AU - Ripoll, C. AU - Mircher, C. AU - Grattau, Y. AU - Olivomarin, J. C. PY - 2012 DA - 2012// TI - Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes JO - Hum Mol Genet VL - 21 UR - https://doi.org/10.1093/hmg/dds142 DO - 10.1093/hmg/dds142 ID - Cossec2012 ER - TY - JOUR AU - Currinn, H. AU - Guscott, B. AU - Balklava, Z. AU - Rothnie, A. AU - Wassmer, T. PY - 2016 DA - 2016// TI - APP controls the formation of PI (3, 5) P 2 vesicles through its binding of the PIKfyve complex JO - Cell Mol Life Sci VL - 73 UR - https://doi.org/10.1007/s00018-015-1993-0 DO - 10.1007/s00018-015-1993-0 ID - Currinn2016 ER - TY - JOUR AU - Czibener, C. AU - Sherer, N. M. AU - Becker, S. M. AU - Pypaert, M. AU - Hui, E. AU - Chapman, E. R. AU - Mothes, W. AU - Andrews, N. W. PY - 2006 DA - 2006// TI - Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes JO - J Cell Biol VL - 174 UR - https://doi.org/10.1083/jcb.200605004 DO - 10.1083/jcb.200605004 ID - Czibener2006 ER - TY - JOUR AU - D'Angelo, G. AU - Vicinanza, M. AU - Campli, A. AU - Matteis, M. A. PY - 2008 DA - 2008// TI - The multiple roles of PtdIns (4) P-not just the precursor of PtdIns (4, 5) P2 JO - J Cell Sci VL - 121 UR - https://doi.org/10.1242/jcs.023630 DO - 10.1242/jcs.023630 ID - D'Angelo2008 ER - TY - JOUR AU - D’Souza, K. AU - Epand, R. M. PY - 2014 DA - 2014// TI - Enrichment of phosphatidylinositols with specific acyl chains JO - Biochim Biophys Acta BBA Biomembr VL - 1838 UR - https://doi.org/10.1016/j.bbamem.2013.10.003 DO - 10.1016/j.bbamem.2013.10.003 ID - D’Souza2014 ER - TY - JOUR AU - Das, R. AU - Balmik, A. A. AU - Chinnathambi, S. PY - 2020 DA - 2020// TI - Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia JO - J Neuroinflamm VL - 17 UR - https://doi.org/10.1186/s12974-019-1694-y DO - 10.1186/s12974-019-1694-y ID - Das2020 ER - TY - JOUR AU - Das, R. AU - Chinnathambi, S. PY - 2020 DA - 2020// TI - Actin-mediated microglial chemotaxis via G-protein coupled purinergic receptor in Alzheimer's disease JO - Neuroscience VL - 448 UR - https://doi.org/10.1016/j.neuroscience.2020.09.024 DO - 10.1016/j.neuroscience.2020.09.024 ID - Das2020 ER - TY - JOUR AU - Deming, P. B. AU - Campbell, S. L. AU - Baldor, L. C. AU - Howe, A. K. PY - 2008 DA - 2008// TI - Protein kinase A regulates 3-phosphatidylinositide dynamics during platelet-derived growth factor-induced membrane ruffling and chemotaxis JO - J Biol Chem VL - 283 UR - https://doi.org/10.1074/jbc.M804448200 DO - 10.1074/jbc.M804448200 ID - Deming2008 ER - TY - JOUR AU - Desale, S. E. AU - Chinnathambi, S. PY - 2020 DA - 2020// TI - Role of dietary fatty acids in microglial polarization in Alzheimer's disease JO - J Neuroinflamm VL - 17 UR - https://doi.org/10.1186/s12974-020-01742-3 DO - 10.1186/s12974-020-01742-3 ID - Desale2020 ER - TY - JOUR AU - Desale, S. E. AU - Chinnathambi, S. PY - 2020 DA - 2020// TI - Role of dietary fatty acids in microglial polarization in Alzheimer’s disease JO - J Neuroinflamm VL - 17 UR - https://doi.org/10.1186/s12974-020-01742-3 DO - 10.1186/s12974-020-01742-3 ID - Desale2020 ER - TY - STD TI - Desale SE, Chinnathamb, S. α-Linoleanic acid modulates phagocytosis of extracellular Tau and induces microglial migration by actin-remodeling; 2020. ID - ref31 ER - TY - JOUR AU - Devreotes, P. AU - Janetopoulos, C. PY - 2003 DA - 2003// TI - Eukaryotic chemotaxis: distinctions between directional sensing and polarization JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.R300010200 DO - 10.1074/jbc.R300010200 ID - Devreotes2003 ER - TY - JOUR AU - DiSabato, D. J. AU - Quan, N. AU - Godbout, J. P. PY - 2016 DA - 2016// TI - Neuroinflammation: the devil is in the details JO - J Neurochem VL - 139 UR - https://doi.org/10.1111/jnc.13607 DO - 10.1111/jnc.13607 ID - DiSabato2016 ER - TY - JOUR AU - Divecha, N. PY - 2010 DA - 2010// TI - Lipid kinases: charging PtdIns (4, 5) P2 synthesis JO - Curr Biol VL - 20 UR - https://doi.org/10.1016/j.cub.2010.01.016 DO - 10.1016/j.cub.2010.01.016 ID - Divecha2010 ER - TY - JOUR AU - Doughman, R. L. AU - Firestone, A. J. AU - Wojtasiak, M. L. AU - Bunce, M. W. AU - Anderson, R. A. PY - 2003 DA - 2003// TI - Membrane ruffling requires coordination between type Iα phosphatidylinositol phosphate kinase and Rac signaling JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M211397200 DO - 10.1074/jbc.M211397200 ID - Doughman2003 ER - TY - JOUR AU - Dowhan, W. PY - 1997 DA - 1997// TI - Molecular basis for membrane phospholipid diversity: why are there so many lipids? JO - Annu Rev Biochem VL - 66 UR - https://doi.org/10.1146/annurev.biochem.66.1.199 DO - 10.1146/annurev.biochem.66.1.199 ID - Dowhan1997 ER - TY - JOUR AU - Dyment, D. A. AU - Smith, A. C. AU - Humphreys, P. AU - Schwartzentruber, J. AU - Beaulieu, C. L. AU - Bulman, D. E. AU - Majewski, J. AU - Woulfe, J. AU - Michaud, J. AU - Boycott, K. M. PY - 2015 DA - 2015// TI - Homozygous nonsense mutation in SYNJ1 associated with intractable epilepsy and tau pathology JO - Neurobiol Aging VL - 36 UR - https://doi.org/10.1016/j.neurobiolaging.2014.09.005 DO - 10.1016/j.neurobiolaging.2014.09.005 ID - Dyment2015 ER - TY - JOUR AU - Fairn, G. D. AU - Ogata, K. AU - Botelho, R. J. AU - Stahl, P. D. AU - Anderson, R. A. AU - Camilli, P. AU - Meyer, T. AU - Wodak, S. AU - Grinstein, S. PY - 2009 DA - 2009// TI - An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis JO - J Cell Biol VL - 187 UR - https://doi.org/10.1083/jcb.200909025 DO - 10.1083/jcb.200909025 ID - Fairn2009 ER - TY - JOUR AU - Fan, Y. AU - Xie, L. AU - Chung, C. Y. PY - 2017 DA - 2017// TI - Signaling pathways controlling microglia chemotaxis JO - Mol Cells VL - 40 ID - Fan2017 ER - TY - JOUR AU - Ferrari, G. AU - Langen, H. AU - Naito, M. AU - Pieters, J. PY - 1999 DA - 1999// TI - A coat protein on phagosomes involved in the intracellular survival of mycobacteria JO - Cell VL - 97 UR - https://doi.org/10.1016/S0092-8674(00)80754-0 DO - 10.1016/S0092-8674(00)80754-0 ID - Ferrari1999 ER - TY - JOUR AU - Gaidarov, I. AU - Smith, M. E. AU - Domin, J. AU - Keen, J. H. PY - 2001 DA - 2001// TI - The class II phosphoinositide 3-kinase C2α is activated by clathrin and regulates clathrin-mediated membrane trafficking JO - Mol Cell VL - 7 UR - https://doi.org/10.1016/S1097-2765(01)00191-5 DO - 10.1016/S1097-2765(01)00191-5 ID - Gaidarov2001 ER - TY - JOUR AU - Gillooly, D. J. AU - Simonsen, A. AU - Stenmark, H. PY - 2001 DA - 2001// TI - Phosphoinositides and phagocytosis JO - J Cell Biol VL - 155 UR - https://doi.org/10.1083/jcb.200109001 DO - 10.1083/jcb.200109001 ID - Gillooly2001 ER - TY - JOUR AU - Gu, Z. AU - Wu, J. AU - Wang, S. AU - Suburu, J. AU - Chen, H. AU - Thomas, M. J. AU - Shi, L. AU - Edwards, I. J. AU - Berquin, I. M. AU - Chen, Y. Q. PY - 2013 DA - 2013// TI - Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells JO - Carcinogenesis VL - 34 UR - https://doi.org/10.1093/carcin/bgt147 DO - 10.1093/carcin/bgt147 ID - Gu2013 ER - TY - JOUR AU - Hammond, G. R. AU - Balla, T. PY - 2015 DA - 2015// TI - Polyphosphoinositide binding domains: key to inositol lipid biology JO - Biochim Biophys Acta BBA Mol Cell Biol Lipids VL - 1851 ID - Hammond2015 ER - TY - JOUR AU - Hampshire, D. J. AU - Ayub, M. AU - Springell, K. AU - Roberts, E. AU - Jafri, H. AU - Rashid, Y. AU - Bond, J. AU - Riley, J. H. AU - Woods, C. G. PY - 2006 DA - 2006// TI - MORM syndrome (mental retardation, truncal obesity, retinal dystrophy and micropenis), a new autosomal recessive disorder, links to 9q34 JO - Eur J Hum Genet EJHG VL - 14 UR - https://doi.org/10.1038/sj.ejhg.5201577 DO - 10.1038/sj.ejhg.5201577 ID - Hampshire2006 ER - TY - JOUR AU - Hardies, K. AU - Cai, Y. AU - Jardel, C. AU - Jansen, A. C. AU - Cao, M. AU - May, P. AU - Djémié, T. AU - Hachon Le Camus, C. AU - Keymolen, K. AU - Deconinck, T. PY - 2016 DA - 2016// TI - Loss of SYNJ1 dual phosphatase activity leads to early onset refractory seizures and progressive neurological decline JO - Brain J Neurol VL - 139 UR - https://doi.org/10.1093/brain/aww180 DO - 10.1093/brain/aww180 ID - Hardies2016 ER - TY - JOUR AU - Hasegawa, J. AU - Strunk, B. S. AU - Weisman, L. S. PY - 2017 DA - 2017// TI - PI5P and PI (3, 5) P2: minor, but essential phosphoinositides JO - Cell Struct Funct VL - 50 ID - Hasegawa2017 ER - TY - JOUR AU - Hayes, M. J. AU - Shao, D. -. M. AU - Grieve, A. AU - Levine, T. AU - Bailly, M. AU - Moss, S. E. PY - 2009 DA - 2009// TI - Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4, 5,-bisphosphate JO - Biochim Biophysica Acta BBA Mol Cell Res VL - 1793 UR - https://doi.org/10.1016/j.bbamcr.2008.10.007 DO - 10.1016/j.bbamcr.2008.10.007 ID - Hayes2009 ER - TY - JOUR AU - Henle, S. J. AU - Wang, G. AU - Liang, E. AU - Wu, M. AU - Poo, M. -. M. AU - Henley, J. R. PY - 2011 DA - 2011// TI - Asymmetric PI (3, 4, 5) P3 and Akt signaling mediates chemotaxis of axonal growth cones JO - J Neurosci VL - 31 UR - https://doi.org/10.1523/JNEUROSCI.0216-11.2011 DO - 10.1523/JNEUROSCI.0216-11.2011 ID - Henle2011 ER - TY - JOUR AU - Heras-Sandoval, D. AU - Avila-Muñoz, E. AU - Arias, C. PY - 2011 DA - 2011// TI - The phosphatidylinositol 3-kinase/mTor pathway as a therapeutic target for brain aging and neurodegeneration JO - Pharmaceuticals VL - 4 UR - https://doi.org/10.3390/ph4081070 DO - 10.3390/ph4081070 ID - Heras-Sandoval2011 ER - TY - CHAP AU - Hilpelä, P. AU - Vartiainen, M. AU - Lappalainen, P. ED - Stenmark, H. PY - 2004 DA - 2004// TI - Regulation of the actin cytoskeleton by PI (4, 5) P 2 and PI (3, 4, 5) P 3 BT - Phosphoinositides in subcellular targeting and enzyme activation PB - Springer CY - New York UR - https://doi.org/10.1007/978-3-642-18805-3_5 DO - 10.1007/978-3-642-18805-3_5 ID - Hilpelä2004 ER - TY - STD TI - Holub B, Kuksis A. Metabolism of molecular species of diacylglycerophospholipids. In: Advances in lipid research. Elsevier; 1978. p. 1–125. ID - ref52 ER - TY - JOUR AU - Janmey, P. A. AU - Bucki, R. AU - Radhakrishnan, R. PY - 2018 DA - 2018// TI - Regulation of actin assembly by PI (4, 5) P2 and other inositol phospholipids: an update on possible mechanisms JO - Biochem Biophys Res Commun VL - 506 UR - https://doi.org/10.1016/j.bbrc.2018.07.155 DO - 10.1016/j.bbrc.2018.07.155 ID - Janmey2018 ER - TY - JOUR AU - Jaumouillé, V. AU - Grinstein, S. PY - 2011 DA - 2011// TI - Receptor mobility, the cytoskeleton, and particle binding during phagocytosis JO - Curr Opin Cell Biol VL - 23 UR - https://doi.org/10.1016/j.ceb.2010.10.006 DO - 10.1016/j.ceb.2010.10.006 ID - Jaumouillé2011 ER - TY - JOUR AU - Jeschke, A. AU - Zehethofer, N. AU - Lindner, B. AU - Krupp, J. AU - Schwudke, D. AU - Haneburger, I. AU - Jovic, M. AU - Backer, J. M. AU - Balla, T. AU - Hilbi, H. PY - 2015 DA - 2015// TI - Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis JO - Proc Natl Acad Sci VL - 112 UR - https://doi.org/10.1073/pnas.1423456112 DO - 10.1073/pnas.1423456112 ID - Jeschke2015 ER - TY - JOUR AU - Jimenez, S. AU - Torres, M. AU - Vizuete, M. AU - Sanchez-Varo, R. AU - Sanchez-Mejias, E. AU - Trujillo-Estrada, L. AU - Carmona-Cuenca, I. AU - Caballero, C. AU - Ruano, D. AU - Gutierrez, A. PY - 2011 DA - 2011// TI - Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3β pathway in Alzheimer mouse model JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M110.209718 DO - 10.1074/jbc.M110.209718 ID - Jimenez2011 ER - TY - JOUR AU - Jope, R. S. AU - Song, L. AU - Powers, R. E. PY - 1997 DA - 1997// TI - Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain JO - Neurobiol Aging VL - 18 UR - https://doi.org/10.1016/S0197-4580(96)00205-9 DO - 10.1016/S0197-4580(96)00205-9 ID - Jope1997 ER - TY - JOUR AU - Kam, T. -. I. AU - Park, H. AU - Gwon, Y. AU - Song, S. AU - Kim, S. -. H. AU - Moon, S. W. AU - Jo, D. -. G. AU - Jung, Y. -. K. PY - 2016 DA - 2016// TI - FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model JO - Elife VL - 5 UR - https://doi.org/10.7554/eLife.18691 DO - 10.7554/eLife.18691 ID - Kam2016 ER - TY - JOUR AU - Layé, S. AU - Nadjar, A. AU - Joffre, C. AU - Bazinet, R. P. PY - 2018 DA - 2018// TI - Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology JO - Pharmacol Rev VL - 70 UR - https://doi.org/10.1124/pr.117.014092 DO - 10.1124/pr.117.014092 ID - Layé2018 ER - TY - JOUR AU - Clainche, C. AU - Carlier, M. -. F. PY - 2008 DA - 2008// TI - Regulation of actin assembly associated with protrusion and adhesion in cell migration JO - Physiol Rev VL - 88 UR - https://doi.org/10.1152/physrev.00021.2007 DO - 10.1152/physrev.00021.2007 ID - Clainche2008 ER - TY - JOUR AU - Levin, R. AU - Grinstein, S. AU - Schlam, D. PY - 2015 DA - 2015// TI - Phosphoinositides in phagocytosis and macropinocytosis JO - Biochem Biophys Acta VL - 1851 ID - Levin2015 ER - TY - JOUR AU - Lung, M. AU - Shulga, Y. V. AU - Ivanova, P. T. AU - Myers, D. S. AU - Milne, S. B. AU - Brown, H. A. AU - Topham, M. K. AU - Epand, R. M. PY - 2009 DA - 2009// TI - Diacylglycerol kinase ϵ is selective for both acyl chains of phosphatidic acid or diacylglycerol JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.050617 DO - 10.1074/jbc.M109.050617 ID - Lung2009 ER - TY - JOUR AU - Madore, C. AU - Leyrolle, Q. AU - Morel, L. AU - Rossitto, M. AU - Greenhalgh, A. D. AU - Delpech, J. C. AU - Martinat, M. PY - 2020 DA - 2020// TI - Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain JO - Nat Commun VL - 11 UR - https://doi.org/10.1038/s41467-020-19861-z DO - 10.1038/s41467-020-19861-z ID - Madore2020 ER - TY - JOUR AU - Madore, C. AU - Nadjar, A. AU - Delpech, J. C. AU - Sere, A. AU - Aubert, A. AU - Portal, C. AU - Joffre, C. AU - Layé, S. PY - 2014 DA - 2014// TI - Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes JO - Brain Behav Immun VL - 41 UR - https://doi.org/10.1016/j.bbi.2014.03.021 DO - 10.1016/j.bbi.2014.03.021 ID - Madore2014 ER - TY - JOUR AU - Matsuda, S. AU - Inoue, T. AU - Lee, H. C. AU - Kono, N. AU - Tanaka, F. AU - Gengyo-Ando, K. AU - Mitani, S. AU - Arai, H. PY - 2008 DA - 2008// TI - Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity JO - Genes Cells VL - 13 UR - https://doi.org/10.1111/j.1365-2443.2008.01212.x DO - 10.1111/j.1365-2443.2008.01212.x ID - Matsuda2008 ER - TY - JOUR AU - Mattila, P. K. AU - Lappalainen, P. PY - 2008 DA - 2008// TI - Filopodia: molecular architecture and cellular functions JO - Nat Rev Mol Cell Biol VL - 9 UR - https://doi.org/10.1038/nrm2406 DO - 10.1038/nrm2406 ID - Mattila2008 ER - TY - JOUR AU - McPherson, P. S. AU - Garcia, E. P. AU - Slepnev, V. I. AU - David, C. AU - Zhang, X. AU - Grabs, D. AU - Sossin, W. S. AU - Bauerfeind, R. AU - Nemoto, Y. AU - Camilli, P. PY - 1996 DA - 1996// TI - A presynaptic inositol-5-phosphatase JO - Nature VL - 379 UR - https://doi.org/10.1038/379353a0 DO - 10.1038/379353a0 ID - McPherson1996 ER - TY - JOUR AU - Mirzaa, G. M. AU - Conway, R. L. AU - Gripp, K. W. AU - Lerman-Sagie, T. AU - Siegel, D. H. AU - Vries, L. S. AU - Lev, D. AU - Kramer, N. AU - Hopkins, E. AU - Graham, J. M. PY - 2012 DA - 2012// TI - Megalencephaly-capillary malformation (MCAP) and megalencephaly-polydactyly-polymicrogyria-hydrocephalus (MPPH) syndromes: two closely related disorders of brain overgrowth and abnormal brain and body morphogenesis JO - Am J Med Genet A VL - 158a UR - https://doi.org/10.1002/ajmg.a.34402 DO - 10.1002/ajmg.a.34402 ID - Mirzaa2012 ER - TY - JOUR AU - Mohammadi, S. AU - Isberg, R. R. PY - 2013 DA - 2013// TI - Cdc42 interacts with the exocyst complex to promote phagocytosis JO - J Cell Biol VL - 200 UR - https://doi.org/10.1083/jcb.201204090 DO - 10.1083/jcb.201204090 ID - Mohammadi2013 ER - TY - JOUR AU - Morel, E. AU - Chamoun, Z. AU - Lasiecka, Z. M. AU - Chan, R. B. AU - Williamson, R. L. AU - Vetanovetz, C. AU - Dall’Armi, C., Simoes, S., Du Jour, K.S.P., and McCabe, B.D. PY - 2013 DA - 2013// TI - Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system JO - Nat Commun VL - 4 UR - https://doi.org/10.1038/ncomms3250 DO - 10.1038/ncomms3250 ID - Morel2013 ER - TY - JOUR AU - Mu, L. AU - Tu, Z. AU - Miao, L. AU - Ruan, H. AU - Kang, N. AU - Hei, Y. AU - Chen, J. AU - Wei, W. AU - Gong, F. AU - Wang, B. PY - 2018 DA - 2018// TI - A phosphatidylinositol 4, 5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing JO - Nat Commun VL - 9 UR - https://doi.org/10.1038/s41467-018-06744-7 DO - 10.1038/s41467-018-06744-7 ID - Mu2018 ER - TY - JOUR AU - Murthy, S. P. AU - Chung, P. H. AU - Lin, L. AU - Lomasney, J. W. PY - 2006 DA - 2006// TI - Activation of phospholipase Cε by free fatty acids and cross talk with phospholipase D and phospholipase A2 JO - Biochemistry VL - 45 UR - https://doi.org/10.1021/bi060648+ DO - 10.1021/bi060648+ ID - Murthy2006 ER - TY - JOUR AU - Nair, S. S. AU - Leitch, J. AU - Garg, M. L. PY - 1999 DA - 1999// TI - Specific modifications of phosphatidylinositol and nonesterified fatty acid fractions in cultured porcine cardiomyocytes supplemented with n-3 polyunsaturated fatty acids JO - Lipids VL - 34 UR - https://doi.org/10.1007/s11745-999-0415-3 DO - 10.1007/s11745-999-0415-3 ID - Nair1999 ER - TY - JOUR AU - Pagnamenta, A. T. AU - Howard, M. F. AU - Wisniewski, E. AU - Popitsch, N. AU - Knight, S. J. AU - Keays, D. A. AU - Quaghebeur, G. AU - Cox, H. AU - Cox, P. AU - Balla, T. PY - 2015 DA - 2015// TI - Germline recessive mutations in PI4KA are associated with perisylvian polymicrogyria, cerebellar hypoplasia and arthrogryposis JO - Hum Mol Genet VL - 24 UR - https://doi.org/10.1093/hmg/ddv117 DO - 10.1093/hmg/ddv117 ID - Pagnamenta2015 ER - TY - JOUR AU - Pomponi, M. F. AU - Gambassi, G. AU - Pomponi, M. AU - Masullo, C. PY - 2010 DA - 2010// TI - Alzheimer’s disease: fatty acids we eat may be linked to a specific protection via low-dose aspirin JO - Aging Dis VL - 1 ID - Pomponi2010 ER - TY - JOUR AU - Quadri, M. AU - Fang, M. AU - Picillo, M. AU - Olgiati, S. AU - Breedveld, G. J. AU - Graafland, J. AU - Wu, B. AU - Xu, F. AU - Erro, R. AU - Amboni, M. PY - 2013 DA - 2013// TI - Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism JO - Hum Mutat VL - 34 UR - https://doi.org/10.1002/humu.22373 DO - 10.1002/humu.22373 ID - Quadri2013 ER - TY - JOUR AU - Raghu, P. AU - Joseph, A. AU - Krishnan, H. AU - Singh, P. AU - Saha, S. PY - 2019 DA - 2019// TI - Phosphoinositides: regulators of nervous system function in health and disease JO - Front Mol Neurosci VL - 12 UR - https://doi.org/10.3389/fnmol.2019.00208 DO - 10.3389/fnmol.2019.00208 ID - Raghu2019 ER - TY - JOUR AU - Ransohoff, R. M. AU - Perry, V. H. PY - 2009 DA - 2009// TI - Microglial physiology: unique stimuli, specialized responses JO - Annu Rev Immunol VL - 27 UR - https://doi.org/10.1146/annurev.immunol.021908.132528 DO - 10.1146/annurev.immunol.021908.132528 ID - Ransohoff2009 ER - TY - JOUR AU - Robinson, F. L. AU - Dixon, J. E. PY - 2005 DA - 2005// TI - The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M505159200 DO - 10.1074/jbc.M505159200 ID - Robinson2005 ER - TY - JOUR AU - Rohatgi, R. AU - Ho, H. -. Y. H. AU - Kirschner, M. W. PY - 2000 DA - 2000// TI - Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate JO - J Cell Biol VL - 150 UR - https://doi.org/10.1083/jcb.150.6.1299 DO - 10.1083/jcb.150.6.1299 ID - Rohatgi2000 ER - TY - JOUR AU - Rozelle, A. AU - Machesky, L. M. AU - Yamamoto, M. AU - Driessens, M. AU - Insall, R. AU - Roth, M. G. AU - Luby-Phelps, K. AU - Marriott, G. AU - Hall, A. AU - Yin, H. L. PY - 2000 DA - 2000// TI - Phosphatidylinositol 4, 5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3 JO - Curr Biol VL - 10 UR - https://doi.org/10.1016/S0960-9822(00)00384-5 DO - 10.1016/S0960-9822(00)00384-5 ID - Rozelle2000 ER - TY - JOUR AU - Ryan, S. D. AU - Whitehead, S. N. AU - Swayne, L. A. AU - Moffat, T. C. AU - Hou, W. AU - Ethier, M. AU - Bourgeois, A. J. AU - Rashidian, J. AU - Blanchard, A. P. AU - Fraser, P. E. PY - 2009 DA - 2009// TI - Amyloid-β42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism JO - Proc Natl Acad Sci VL - 106 UR - https://doi.org/10.1073/pnas.0905654106 DO - 10.1073/pnas.0905654106 ID - Ryan2009 ER - TY - JOUR AU - Saarikangas, J. AU - Zhao, H. AU - Lappalainen, P. PY - 2010 DA - 2010// TI - Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides JO - Physiol Rev VL - 90 UR - https://doi.org/10.1152/physrev.00036.2009 DO - 10.1152/physrev.00036.2009 ID - Saarikangas2010 ER - TY - JOUR AU - Sarkes, D. AU - Rameh, L. E. PY - 2010 DA - 2010// TI - A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5 P and other phosphoinositides JO - Biochem J VL - 428 UR - https://doi.org/10.1042/BJ20100129 DO - 10.1042/BJ20100129 ID - Sarkes2010 ER - TY - JOUR AU - Sarlus, H. AU - Heneka, M. T. PY - 2017 DA - 2017// TI - Microglia in Alzheimer’s disease JO - J Clin Investig VL - 127 UR - https://doi.org/10.1172/JCI90606 DO - 10.1172/JCI90606 ID - Sarlus2017 ER - TY - JOUR AU - Schlam, D. AU - Bagshaw, R. D. AU - Freeman, S. A. AU - Collins, R. F. AU - Pawson, T. AU - Fairn, G. D. AU - Grinstein, S. PY - 2015 DA - 2015// TI - Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins JO - Nat Commun VL - 6 UR - https://doi.org/10.1038/ncomms9623 DO - 10.1038/ncomms9623 ID - Schlam2015 ER - TY - JOUR AU - Scott, C. C. AU - Dobson, W. AU - Botelho, R. J. AU - Coady-Osberg, N. AU - Chavrier, P. AU - Knecht, D. A. AU - Heath, C. AU - Stahl, P. AU - Grinstein, S. PY - 2005 DA - 2005// TI - Phosphatidylinositol-4, 5-bis phosphate hydrolysis directs actin remodeling during phagocytosis JO - J Cell Biol VL - 169 UR - https://doi.org/10.1083/jcb.200412162 DO - 10.1083/jcb.200412162 ID - Scott2005 ER - TY - JOUR AU - Shulga, Y. V. AU - Myers, D. S. AU - Ivanova, P. T. AU - Milne, S. B. AU - Brown, H. A. AU - Topham, M. K. AU - Epand, R. M. PY - 2010 DA - 2010// TI - Molecular species of phosphatidylinositol-cycle intermediates in the endoplasmic reticulum and plasma membrane JO - Biochemistry VL - 49 UR - https://doi.org/10.1021/bi901551e DO - 10.1021/bi901551e ID - Shulga2010 ER - TY - JOUR AU - Simons, J. P. AU - Al-Shawi, R. AU - Minogue, S. AU - Waugh, M. G. AU - Wiedemann, C. AU - Evangelou, S. AU - Loesch, A. AU - Sihra, T. S. AU - King, R. AU - Warner, T. T. PY - 2009 DA - 2009// TI - Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axons JO - Proc Natl Acad Sci USA VL - 106 UR - https://doi.org/10.1073/pnas.0903011106 DO - 10.1073/pnas.0903011106 ID - Simons2009 ER - TY - JOUR AU - Sonawane, S. K. AU - Chinnathambi, S. PY - 2018 DA - 2018// TI - Prion-like propagation of post-translationally modified tau in Alzheimer’s disease: a hypothesis JO - J Mol Neurosci VL - 65 UR - https://doi.org/10.1007/s12031-018-1111-5 DO - 10.1007/s12031-018-1111-5 ID - Sonawane2018 ER - TY - JOUR AU - Španić, E. AU - Langer Horvat, L. AU - Hof, P. R. AU - Simic, G. PY - 2019 DA - 2019// TI - Role of microglial cells in Alzheimer’s disease tau propagation JO - Front Aging Neurosci VL - 11 UR - https://doi.org/10.3389/fnagi.2019.00271 DO - 10.3389/fnagi.2019.00271 ID - Španić2019 ER - TY - JOUR AU - Sperling, R. I. AU - Benincaso, A. I. AU - Knoell, C. T. AU - Larkin, J. K. AU - Austen, K. F. AU - Robinson, D. R. PY - 1993 DA - 1993// TI - Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils JO - J Clin Investig VL - 91 UR - https://doi.org/10.1172/JCI116245 DO - 10.1172/JCI116245 ID - Sperling1993 ER - TY - JOUR AU - Stark, K. D. AU - Elswyk, M. E. AU - Higgins, M. R. AU - Weatherford, C. A. AU - Salem, N. PY - 2016 DA - 2016// TI - Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults JO - Prog Lipid Res VL - 63 UR - https://doi.org/10.1016/j.plipres.2016.05.001 DO - 10.1016/j.plipres.2016.05.001 ID - Stark2016 ER - TY - JOUR AU - Strosznajder, J. PY - 2003 DA - 2003// TI - Phosphoinositides kinases in brain aging and amyloid beta neurotoxicity JO - J Neurochem VL - 85 UR - https://doi.org/10.1046/j.1471-4159.85.s2.11_4.x DO - 10.1046/j.1471-4159.85.s2.11_4.x ID - Strosznajder2003 ER - TY - JOUR AU - Strosznajder, J. B. AU - Zambrzycka, A. AU - Kacprzak, M. D. AU - Strosznajder, R. P. PY - 1999 DA - 1999// TI - Amyloid β peptide 25–35 modulates hydrolysis of phosphoinositides by membrane phospholipase (s) C of adult brain cortex JO - J Mol Neurosci VL - 12 UR - https://doi.org/10.1007/BF02736924 DO - 10.1007/BF02736924 ID - Strosznajder1999 ER - TY - JOUR AU - Tanaka, T. AU - Tsujio, I. AU - Nishikawa, T. AU - Shinosaki, K. AU - Kudo, T. AU - Takeda, M. PY - 2000 DA - 2000// TI - Significance of tau phosphorylation and protein kinase regulation in the pathogenesis of Alzheimer disease JO - Alzheimer Dis Assoc Disord VL - 14 UR - https://doi.org/10.1097/00002093-200000001-00004 DO - 10.1097/00002093-200000001-00004 ID - Tanaka2000 ER - TY - JOUR AU - Tang, X. AU - Edwards, E. M. AU - Holmes, B. B. AU - Falck, J. R. AU - Campbell, W. B. PY - 2006 DA - 2006// TI - Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta JO - Am J Physiol Heart Circ Physiol VL - 290 UR - https://doi.org/10.1152/ajpheart.00491.2005 DO - 10.1152/ajpheart.00491.2005 ID - Tang2006 ER - TY - JOUR AU - Uranga, R. M. AU - Alza, N. P. AU - Conde, M. A. AU - Antollini, S. S. AU - Salvador, G. A. PY - 2017 DA - 2017// TI - Phosphoinositides: two-path signaling in neuronal response to oligomeric amyloid β peptide JO - Mol Neurobiol VL - 54 UR - https://doi.org/10.1007/s12035-016-9885-3 DO - 10.1007/s12035-016-9885-3 ID - Uranga2017 ER - TY - JOUR AU - Bout, I. AU - Divecha, N. PY - 2009 DA - 2009// TI - PIP5K-driven PtdIns (4, 5) P2 synthesis: regulation and cellular functions JO - J Cell Sci VL - 122 UR - https://doi.org/10.1242/jcs.056127 DO - 10.1242/jcs.056127 ID - Bout2009 ER - TY - JOUR AU - Vanhaesebroeck, B. AU - Guillermet-Guibert, J. AU - Graupera, M. AU - Bilanges, B. PY - 2010 DA - 2010// TI - The emerging mechanisms of isoform-specific PI3K signalling JO - Nat Rev Mol Cell Biol VL - 11 UR - https://doi.org/10.1038/nrm2882 DO - 10.1038/nrm2882 ID - Vanhaesebroeck2010 ER - TY - JOUR AU - Wallace, M. A. PY - 1994 DA - 1994// TI - Effects of Alzheimer's disease-related β amyloid protein fragments on enzymes metabolizing phosphoinositides in brain JO - Biochim Biophys Acta BBA Mol Basis Dis VL - 1227 UR - https://doi.org/10.1016/0925-4439(94)90093-0 DO - 10.1016/0925-4439(94)90093-0 ID - Wallace1994 ER - TY - JOUR AU - Williams, C. M. AU - Maunder, K. PY - 1992 DA - 1992// TI - Effect of dietary fatty acid composition on inositol-, choline-and ethanolamine-phospholipids of mammary tissue and erythrocytes in the rat JO - Br J Nutr VL - 68 UR - https://doi.org/10.1079/BJN19920076 DO - 10.1079/BJN19920076 ID - Williams1992 ER - TY - JOUR AU - Zhang, S. -. X. AU - Duan, L. -. H. AU - He, S. -. J. AU - Zhuang, G. -. F. AU - Yu, X. PY - 2017 DA - 2017// TI - Phosphatidylinositol 3, 4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation JO - Cell Res VL - 27 UR - https://doi.org/10.1038/cr.2017.13 DO - 10.1038/cr.2017.13 ID - Zhang2017 ER - TY - JOUR AU - Zhang, Y. AU - Cao, F. AU - Zhou, Y. AU - Feng, Z. AU - Sit, B. AU - Krendel, M. AU - Yu, C. -. H. PY - 2019 DA - 2019// TI - Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes JO - Mol Biol Cell VL - 30 UR - https://doi.org/10.1091/mbc.E18-06-0398 DO - 10.1091/mbc.E18-06-0398 ID - Zhang2019 ER - TY - JOUR AU - Zhang, Y. AU - Sloan, S. A. AU - Clarke, L. E. AU - Caneda, C. AU - Plaza, C. A. AU - Blumenthal, P. D. AU - Vogel, H. AU - Steinberg, G. K. AU - Edwards, M. S. AU - Li, G. PY - 2016 DA - 2016// TI - Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse JO - Neuron VL - 89 UR - https://doi.org/10.1016/j.neuron.2015.11.013 DO - 10.1016/j.neuron.2015.11.013 ID - Zhang2016 ER - TY - JOUR AU - Zhao, L. AU - Xiao, Y. AU - Xiu, J. AU - Tan, L. -. C. AU - Guan, Z. -. Z. PY - 2018 DA - 2018// TI - Protection against the neurotoxic effects of β-amyloid peptide on cultured neuronal cells by lovastatin involves elevated expression of α7 nicotinic acetylcholine receptors and activating phosphorylation of protein kinases JO - Am J Pathol VL - 188 UR - https://doi.org/10.1016/j.ajpath.2017.11.020 DO - 10.1016/j.ajpath.2017.11.020 ID - Zhao2018 ER - TY - JOUR AU - Zolov, S. N. AU - Bridges, D. AU - Zhang, Y. AU - Lee, W. W. AU - Riehle, E. AU - Verma, R. AU - Lenk, G. M. AU - Converso-Baran, K. AU - Weide, T. AU - Albin, R. L. PY - 2012 DA - 2012// TI - In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P JO - Proc Natl Acad Sci USA VL - 109 UR - https://doi.org/10.1073/pnas.1203106109 DO - 10.1073/pnas.1203106109 ID - Zolov2012 ER -