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Table 1 Optimized parameter values for the different models

From: L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness

  Single model
Parameter value (± SD)
BT-20 model
Parameter value (± SD)
HCC38 model
Parameter value (± SD)
MCF7 model
Parameter value (± SD)
SKBR3 model
Parameter value (± SD)
Final model
Parameter value (± SD)
p70S6K- > LPL 0.02 (± 0.03) 0.01 (± 0.04) 0.01 (± 0.01) 0.00 (± 0.02) 0.01 (± 0.06) 0.00 (± 0.00)
PKA- > LPL 0.02 (± 0.04) 0.01 (± 0.05) 0.08 (± 0.05) 0.13 (± 0.07) 0.08 (± 0.02) 0.13 (± 0.07)
PKC- > LPL 0.02 (± 0.04) 0.01 (± 0.05) 0.08 (± 0.05) 0.13 (± 0.07) 0.08 (± 0.02) 0.13 (± 0.07)
RSK- > LPL 0.50 (± 0.15) 0.72 (± 0.20) 0.79 (± 0.08) 0.74 (± 0.10) 0.35 (± 0.12) 0.28 (± 0.05)
SGK- > LPL 0.43 (± 0.14) 0.25 (± 0.16) 0.05 (± 0.09) 0.00 (± 0.18) 0.49 (± 0.16) 0.46 (± 0.14)