Fig. 1
From: Tumor microenvironment complexity and therapeutic implications at a glance
Tumor microenvironment at a glance. Tumor cells hijack different cellular and non-cellular non-malignant components of TME to promote their own growth and survival under hostile conditions. Meanwhile, the mediators for such contacts can be soluble factors (chemokines/cytokines/growth factors, etc.), or those that enable horizontal genetic/biomaterial transfer including cfDNA, apoptotic bodies, CTCs, and exosomes