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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity

Fig. 9

Effects of FA and GW4064 (FXR agonist) on FXR-CREB1 pathway and autophagy in yellow catfish hepatocytes at 48 h. a Flow cytometric analysis and relative mean fluorescence intensity of LysoTracker and AO staining. b Expression of genes involved in autophagy. GW, GW4064. FA, oleic and palmitic acid at a ratio of 1:1. Values are means ± SEM (n = 3). Asterisks (∗) indicate significant differences between the two groups (p < 0.05)

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