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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I

Fig. 5

Inhibitory Effect of ME on 4NQO-induced oral cancer. a Representative images of 4NQO induced lesions. b Tumor area per mouse from 4NQO only (control) mice versus those treated with ME or individual agents from ME (n = 15). c Body weights of mice following the full duration of treatment with ME or its individual agents. d Representative IHC images for Ki-67. e Quantitation of Ki-67 from IHC analysis of animals. f Representative colorized T2w MRI scans of 4NQO mice (a) without and (b) with ME treatment. The lesion in the untreated mouse is encircled. *P < 0.05; **P < 0.01

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